Beschreibung
Peptic ulcer is one the most serious diseases over wide the world. Most classic treatment lines produce adverse drug reactions. Therefore, this study aimed to investigate the protective effects of two natural extracts, namely ginger and marshmallow extracts, on peptic ulcer induced experimentally in rats compared to famotidine as a reference anti-ulcer agent. In the present study, two different models of animal experiments have been involved. The first was rat pyloric ligation-induced gastric ulceration model. The second model of experiments was indomethacin-induced gastric ulceration in rats. Results demonstrate that administration of either ginger or marshmallow extracts could protect against pyloric ligation-induced peptic ulcer and indomethacin-induced peptic ulcer in rats presumably via their antioxidant properties, being promising for further clinical trials.
Autorenporträt
Sameh Saad Zaghlool Ahmed Abdel-Ghany is working as Assistant Lecturer in Pharmacology and Toxicology Department, Faculty of Pharmacy, Nahda University, Egypt. He has obtained his Master degree in Pharmacology and Toxicology in 2014 from Faculty of Pharmacy, Beni-Sueif University, Egypt. He is the author of several articles published in reputed journals.
