Gabapentin taste masking using -cyclodextrin: An in vitro evaluation

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Gabapentin: Not bitter now

ISBN: 6200440417
ISBN 13: 9786200440419
Autor: Kumar, Kapil/Poswal, Rajesh
Verlag: LAP LAMBERT Academic Publishing
Umfang: 84 S.
Erscheinungsdatum: 03.11.2019
Auflage: 1/2019
Format: 0.6 x 22 x 15
Gewicht: 143 g
Produktform: Kartoniert
Einband: Kartoniert
Artikelnummer: 8193173 Kategorie:

Beschreibung

Gabapentin is a bitter drug used for treatment of epilepsy. It is now also used for neuronal pain. This book explain about masking of gabapentin bitterness using cyclodextrin. First of all, drug profile and excipient profile was studied. All necessary evaluation and interpretation about purity, characterization was done using FTIR and other organoleptic properties. Various batches were formed using various concentration of polymer. Finally B-cyclodextrin was found suitable polymer for masking the bitterness with desired pharmacological activity and drug release.

Autorenporträt

Dr. Kapil Kumar holding a position of Assistant Professor at School of Pharmacy and Technology Management, SVKM's NMIMS, Hyderabad, India. His research interest is towards the synthesis of new chemical entity for pharmacological activity. He is actively involved in drug discovery and development process.

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