Synthesis and characterization of Triazolo[4,3-c]pyrimidine library

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39,90 

ISBN: 3659639850
ISBN 13: 9783659639852
Autor: Vilapara, Dr Kalpesh/Gami, Dr Sagar
Herausgeber: Yogesh Naliapara
Verlag: LAP LAMBERT Academic Publishing
Umfang: 88 S.
Erscheinungsdatum: 26.08.2019
Auflage: 1/2019
Format: 0.6 x 22 x 15
Gewicht: 149 g
Produktform: Kartoniert
Einband: Kartoniert
Artikelnummer: 7921260 Kategorie:

Beschreibung

A novel [1,2,4]triazolo[4,3-c]pyrimidine-8-carboxamide libraries were synthesized via oxidative cyclization of hydrazono-1,6-dihydropyrimidine-5-carboxamide intermediates by the application of Iodobenzenediacetate as a sole cyclizating agent. Here, we report one pot sequential strategy to generate corresponding triazolopyrimidines by condensation of preprepared -acylketene dithioacetals and arylamidines. Moreover, this process describes the application of presynthesized arylamidines which omits the transition metal catalyzed Suzuki-Miyaura cross coupling reaction hence signify the atom- and step-economic methodology.

Autorenporträt

Dr. Kalpesh VilaparaM.Sc., Ph.D. Chemistry,Saurashtra University,Rajkot-360005

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