Mathematical, Computational and Experimental T Cell Immunology

Lieferzeit: Lieferbar innerhalb 14 Tagen

235,39 

ISBN: 3030572064
ISBN 13: 9783030572068
Herausgeber: Carmen Molina-París/Grant Lythe
Verlag: Springer Verlag GmbH
Umfang: x, 298 S., 15 s/w Illustr., 59 farbige Illustr., 298 p. 74 illus., 59 illus. in color.
Erscheinungsdatum: 06.01.2022
Auflage: 1/2022
Produktform: Kartoniert
Einband: Kartoniert

The purpose of this book is to present current mathematical and computational models that are used to describe and characterise the immunology of T cells. The reader will be exposed to a variety of tools/methods that go hand-in-hand with the T cell-mediated immunological process that is being modelled.We aim in the proposed book to emphasise the role that mathematical (or computational) modelling has already played in Immunology. Each chapter will provide an example of the contribution of mathematics to T cell immunology under one of the following four headings:i) Generation of hypotheses,ii) Quantification of immunological processes,iii) Definition of observables to measure given an experimental objective,iv) reconciling disparate (or even conflicting) experimental results.

Artikelnummer: 3163100 Kategorie:

Beschreibung

Mathematical, statistical, and computational methods enable multi-disciplinary approaches that catalyse discovery. Together with experimental methods, they identify key hypotheses, define measurable observables and reconcile disparate results. This volume collects a representative sample of studies in T cell immunology that illustrate the benefits of modelling-experimental collaborations and which have proven valuable or even ground-breaking. Studies include thymic selection, T cell repertoire diversity, T cell homeostasis in health and disease, T cell-mediated immune responses, T cell memory, T cell signalling and analysis of flow cytometry data sets. Contributing authors are leading scientists in the area of experimental, computational, and mathematical immunology. Each chapter includes state-of-the-art and pedagogical content, making this book accessible to readers with limited experience in T cell immunology and/or mathematical and computational modelling.

Autorenporträt

Grant Lythe and Carmen Molina-París are Professors of Applied Mathematics at the University of Leeds. They have coordinated the FP7 Initial Training Network on Quantitative T cell Immunology (2013-2017) and they currently coordinate the H2020 Innovative Training Network on Quantitative T cell Immunology and Immunotherapy (2018-2022).

Herstellerkennzeichnung:


Springer Verlag GmbH
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69121 Heidelberg
DE

E-Mail: juergen.hartmann@springer.com

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