Produktbild: Experimental Models of Parkinsons Disease

Experimental Models of Parkinsons Disease

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139,09 €

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Methods in Molecular Biology 2322

ISBN: 1071614975
ISBN 13: 9781071614976
Herausgeber: Yuzuru Imai
Verlag: Springer Verlag GmbH
Umfang: xi, 217 S., 10 s/w Illustr., 47 farbige Illustr., 217 p. 57 illus., 47 illus. in color.
Erscheinungsdatum: 29.05.2022
Auflage: 1/2022
Produktform: Kartoniert
Einband: Kartoniert

This detailed book focuses on cutting-edge methods for Parkinson’s disease (PD) research, such as the analysis of the prion-like properties of a-synuclein, mitochondrial functions related to the PINK1-Parkin pathway/CHCHD2, the endolysosome pathway related to LRRK2, VPS35, and ATP13A2 using cultured cells (including patient iPS cells), deep brain stimulation therapy, classic mitochondrial toxins related to PD, and genetic associations and screenings using mammalian and invertebrate genetic models of PD. The collection intends to serve as an introductory protocol book for basic research on PD pathogenesis. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Experimental Models of Parkinson’s Disease is an ideal guide for researchers continuing to work toward making PD risk predictable and surmountable.

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