Dopaminergic Neuron Transplantation in the Weaver Mouse Model of Parkinsons Disease

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Advances in Experimental Medicine and Biology 517

ISBN: 0306474352
ISBN 13: 9780306474354
Autor: Triarhou, Lazaros C
Verlag: Springer Verlag GmbH
Umfang: x, 148 S.
Erscheinungsdatum: 31.01.2003
Produktform: Gebunden/Hardback
Einband: GEB

Marks the culmination of research on the transplantation of dopaminergic neurons in the striatum of the weaver mouse, a neurological mutant characterized by genetically-determined degeneration of midbrain dopamine neurons. This book reviews structural and functional aspects of intrastriatal mesencephalic neuron grafting into the weaver model.

Artikelnummer: 1536826 Kategorie:

Beschreibung

transplantations.

Inhaltsverzeichnis

Preface. Acknowledgements. 1. Introduction. 2. Biology and Pathology of the Weaver Mutant Mouse. 3. Histochemical Properties of Intrastriatal Mesencephalic Grafts. 4. Structural Correlates of Process Outgrowth and Circuit Reconstruction. 5. Neurochemical Indices of Functional Restoration. 6. Behavioral Recovery of Functional Responses. 7. Directions for Future Research. Index.

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