Beschreibung
Coenzyme Q10 plays a pivotal role in mitochondrial respiratory chain for cell power supply. Coenzyme Q10 serves as a physiological electron (e-) shuttle from complexes I and II to complex III, as well as a potent antioxidant. In different types of neurological disorders, dysfunction of the respiratory chain leads to reduced ATP levels and increased generation of reactive oxygen species. Coenzyme Q10 supplementation has been widely used in such targeted therapies, including aging, stroke, neuromuscular diseases, Parkinsons disease, Alzheimer's disease, progressive supranuclear palsy, autosomal recessive cerebellar ataxias, amyotrophic lateral sclerosis and Huntingtons disease. This book summarized a large number of experimental and clinical trials for Coenzyme Q10 based therapies in Neurology.
Autorenporträt
He has authored over 60 scientific papers and is the recipient of several international honors and awards. His research aims at understanding the mechanisms that control brain plasticity in order to develop new treatments and cures for neurological and psychiatric disorders.