Gap Junctions in Development and Disease

Lieferzeit: Lieferbar innerhalb 14 Tagen

160,49 €

inkl. 7 % MwSt. zzgl. Versandkosten

ISBN: 3642065597
ISBN 13: 9783642065590
Herausgeber: Elke Winterhager
Verlag: Springer Verlag GmbH
Umfang: XVII, 279 S., 37 s/w Illustr., 10 farbige Illustr., 279 p. 47 illus., 10 illus. in color.
Erscheinungsdatum: 14.10.2010
Auflage: 1/2005
Produktform: Kartoniert
Einband: KT

The main objective of Gap Junctions in Development and Disease is to describe the molecular events that cause impairments in development and disease. Communication between cells via intercellular channels, so called gap junctions, appears to be essential for certain developmental processes and appropriate organ function. Starting with a comprehensive review of the various mouse and human genes encoding the channel-forming protein connexin, further chapters describe the most important connexin mutations that lead to diseases such as hereditary deafness and female infertility in humans. Erroneous signaling mediated via connexin-protein interactions, thought to be responsible for disfunction of organs such as heart, muscle, brain, skin, lens, placenta, and endocrine tissue in mice and men, is also addressed. Although the question why some of the mutations in gap-junction proteins lead to a specific phenotype remains to be answered, the reviews in this book give an intriguing outlook on the future direction of this research field.

Artikelnummer: 1607914 Kategorie:

Beschreibung

Inhaltsangabe1 Connexin and Pannexin Genes in the Mouse and Human Genome Klaus Willecke, Jürgen Eiberger and Julia von Maltzahn 2 Essential Role of Gap Junctions during Development and Regeneration of Skeletal Muscle Julia von Maltzahn and Klaus Willecke 3 Connexins in Cardiac Development: Expression, Role, and Transcriptional Control Daniel B. Gros, S. Alcoléa, L. Dupays, S. Meysen, L. Miquerol, M. Théveniau-Ruissy, BEJ Teunissen, MFA Bierhuizen 4 Gap Junction and Connexin Remodelling in Human Heart Disease Nicholas J. Severs, Emmanuel Dupont, Riyaz Kaba and Neil Thomas 5 Gap Junction Expression in Brain Tissues with Focus on Development Rolf Dermietzel and Carola Meier 6 Connexins Responsible for Hereditary Deafness - The Tale Unfolds Martine Cohen-Salmon, Francisco J. del Castillo, and Christine Petit 7 Human Connexins in Skin Development and Skin Disorders Gabriele Richard 8 Intercellular Communication in Lens Development and Disease Adam M. DeRosa, Francisco J. Martinez-Wittinghan, Richard T. Mathias, Thomas W. White 9 Connexin Modulators of Endocrine Function Philippe Klee, Nathalie Boucard, Dorothée Caille, José Cancela, Anne Charollais, Eric Charpantier, Laetitia Michon, Céline Populaire, Manon Peyrou, Rachel Nlend Nlend, Laurence Zulianello, Jacques-Antoine Haefliger, and Paolo Meda 10 Roles of Gap Junctions in Ovarian Folliculogenesis: Implications for Female Infertility Gerald M. Kidder 11 Placental Connexins of Mice and Men Caroline Dunk, Mark Kibschull, Alexandra Gellhaus, Elke Winterhager and Stephen Lye 12 Connexins in Growth Control and Cancer Christian C. Naus, Gary S. Goldberg and Wun Chey Sin

Inhaltsverzeichnis

1 Connexin and Pannexin Genes in the Mouse and Human Genome Klaus Willecke, Jürgen Eiberger and Julia von Maltzahn 2 Essential Role of Gap Junctions during Development and Regeneration of Skeletal Muscle Julia von Maltzahn and Klaus Willecke 3 Connexins in Cardiac Development: Expression, Role, and Transcriptional Control Daniel B. Gros, S. Alcolea, L. Dupays, S. Meysen, L. Miquerol, M. Theveniau-Ruissy, BEJ Teunissen, MFA Bierhuizen 4 Gap Junction and Connexin Remodelling in Human Heart Disease Nicholas J. Severs, Emmanuel Dupont, Riyaz Kaba and Neil Thomas 5 Gap Junction Expression in Brain Tissues with Focus on Development Rolf Dermietzel and Carola Meier 6 Connexins Responsible for Hereditary Deafness - The Tale Unfolds Martine Cohen-Salmon, Francisco J. del Castillo, and Christine Petit 7 Human Connexins in Skin Development and Skin Disorders Gabriele Richard 8 Intercellular Communication in Lens Development and Disease Adam M. DeRosa, Francisco J. Martinez-Wittinghan, Richard T. Mathias, Thomas W. White 9 Connexin Modulators of Endocrine Function Philippe Klee, Nathalie Boucard, Dorothee Caille, Jose Cancela, Anne Charollais, Eric Charpantier, Laetitia Michon, Celine Populaire, Manon Peyrou, Rachel Nlend Nlend, Laurence Zulianello, Jacques-Antoine Haefliger, and Paolo Meda 10 Roles of Gap Junctions in Ovarian Folliculogenesis: Implications for Female Infertility Gerald M. Kidder 11 Placental Connexins of Mice and Men Caroline Dunk, Mark Kibschull, Alexandra Gellhaus, Elke Winterhager and Stephen Lye 12 Connexins in Growth Control and Cancer Christian C. Naus, Gary S. Goldberg and Wun Chey Sin

Das könnte Ihnen auch gefallen …