Tight Junctions in Cancer Metastasis

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160,49 

Cancer Metastasis – Biology and Treatment 19

ISBN: 9400760272
ISBN 13: 9789400760271
Herausgeber: Tracey A Martin/Wen G Jiang
Verlag: Springer Verlag GmbH
Umfang: viii, 313 S.
Erscheinungsdatum: 09.03.2013
Auflage: 1/2013
Produktform: Gebunden/Hardback
Einband: GEB

This book summarizes current knowledge of tight junctions and their role in cancer and cancer metastasis. Coverage includes fundamental changes in tight junctions in the process of cancer development and the importance of cellular structure in drug therapy.

Artikelnummer: 4136227 Kategorie:

Beschreibung

InhaltsangabePreface. 1. The molecular aspects of Tight junctions2. The distribution of tight junctions and junctional proteins in the body3. Methods to study Tight Junctions4. Enhanced vascular permeability in solid tumors: A promise for Anticancer Nanomedicine5.Tight junctions, Junctional Adhesion Molecules (JAMs), and the blood brain barrier.6. Tight Junctions in human urinary bladder cancer7. Tight junctions in colorectal cancer8. Tight Junctions in breast cancer: multifaceted players in tumorigenesis and progression9.Regulation of tight junctions for therapeutic advantages10.VEGF-Mediated Effects On Brain Microvascular Endothelial Tight Junctions and Transmigration of Breast Cancer Cells Across The Blood-Brain Barrier 11. Claudin-5 and cancer metastasis12. Signaling pathways regulating endothelial cell-cell junctions as a barrier to tumor cell metastasis13. The ROCK signalling pathway and Tight JunctionsIndex.

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