Development of Pathway-based Method for Analysis of Metabolic Network

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Integration of Heterogeneous Biological Data into a Complex Metabolic Network

ISBN: 3659859346
ISBN 13: 9783659859342
Autor: Badsha, Md Bahadur
Verlag: LAP LAMBERT Academic Publishing
Umfang: 124 S.
Erscheinungsdatum: 02.04.2016
Auflage: 1/2016
Format: 0.9 x 22 x 15
Gewicht: 203 g
Produktform: Kartoniert
Einband: Kartoniert
Artikelnummer: 9303564 Kategorie:

Beschreibung

The major human diseases like as diabetes, obesity, high blood pressure, cardiovascular disease and cancer are involved in failure of human metabolic systems. Therefore, metabolism is an important biological process, but these are complex and highly interconnected each others. The challenge becomes how to integrate this data to maximize the amount of useful biological information that can be extracted. A serious problem of pathway-based analysis is that the computational time increases exponentially with an increase in network sizes, which makes the computation of the all pathway expensive and impracticable for large- or genome-scale networks. To address such aforementioned problem, we developed a pathway-based analysis complementary elementary mode, exposed a new window for a large-scale metabolic network, greatly reducing the computational time and memory cost. This book greatly attracts a broad range of scientists who are interested in systems biotechnology, synthetic biology, and bioinformatics, because it provides a method critically useful for analysis of a large-scale metabolic network map.

Autorenporträt

He completed PhD from Japan in 2015. He is working as a postdoctoral researcher in, Japan. From May, 2016 he will join as a postdoctoral researcher at the University of Idaho, Moscow, U.S.A. He has published more than 30 articles including conferences. His research interests in Computational Biology and Bioinformatics.

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