Beschreibung
Metabolic engineering is a rapidly evolving field that is being applied for the optimization of many different industrial processes. In this issue of Advances in Biochemical Engineering/Biotechnology, developments in different areas of metabolic engineering are reviewed. The contributions discuss the application of metabolic engineering in the improvement of yield and productivity - illustrated by amino acid production and the production of novel compounds - in the production of polyketides and extension of the substrate range - and in the engineering of S. cerevisiae for xylose metabolism, and the improvement of a complex biotransformation process.
Inhaltsverzeichnis
G. Stephanopoulos, R.T. Gill: After a Decade of Progress, an Expanded Role for Metabolic Engineering.- A.A. de Graaf, L. Eggeling, H. Sahm: Metabolic Engineering for L-Lysine Production by Corynebacterium glutamicum.- R. McDaniel, P. Licari, C. Khosla: Process Development and Metabolic Engineering for the Overproduction of Natural and Unnatural Polyketides.- B. Hahn-Hägerdal, D.F. Wahlbom, M. Gardonyi, W.H. van Zyl, R.R. Cordero Otero, L.J. Jönsson: Metabolic Engineering of Saccharomyces cerevisiae for Xylose Utilization.- D.E. Stafford, K.S. Yanagimachi, G. Stephanopoulos: Metabolic Engineering of Indene Bioconversion in Rhodococcus sp..- M. McIntyre, C. Müller, J. Dynesen, J. Nielsen: Metabolic Engineering of the Morphology of Aspergillus.- U. Sauer: Evolutionary Engineering of Industrially Important Microbial Phenotypes.
