The Metabolic Syndrome:

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Epidemiology, Clinical Treatment, and Underlying Mechanisms, Contemporary Endocrinology

ISBN: 1617377503
ISBN 13: 9781617377501
Herausgeber: Barbara C Hansen/George A Bray
Verlag: Humana Press
Umfang: xii, 402 S.
Erscheinungsdatum: 09.11.2010
Auflage: 1/2008
Produktform: Kartoniert
Einband: KT

With an extraordinary need for early intervention and prevention to slow or halt its progression, Metabolic Syndrome is one of the most challenging health problems. Only through an understanding of the science underlying this syndrome can successful interventions be developed and implemented. In The Metabolic Syndrome: Epidemiology, Clinical Treatment, and Underlying Mechanisms, the writers stimulate new thinking concerning underlying mechanisms and encourage heightened efforts to develop new therapeutics, potentially targeting uniquely intersecting pathways. Developing this new synthesis and analysis of the Metabolic Syndrome will bring together the viewpoints of epidemiologists, physiologists, molecular biologists/biochemists, and clinicians toward understanding the current state of knowledge of both the causes and consequences of the Metabolic Syndrome.

Artikelnummer: 985120 Kategorie:

Beschreibung

InhaltsangabePart I: Epidemiology and Clinical Treatment: Issues in defining and treating the metabolic syndrome Chapter 1 Metabolic Syndrome: to be or not to be? Gerald M. Reaven Chapter 2 The Role of Obesity in Insulin Resistance: Epidemiological and metabolic aspects James B. Meigs Chapter 3 Treatment of the Metabolic Syndrome with Weight Loss, Exercise, Hormones, and Surgery George A. Bray Chapter 4 Insulin Resistance, Metabolic Syndrome, and Cardiovascular Disease: an epidemiological perspective Earl Ford and Simin Liu Chapter 5 The Sympatho-Adrenal System in Metabolic Syndrome Lewis Landsberg Part II: Endothelial Function, Inflammation, and Dyslipidemia Chapter 6 Insulin Action and Endothelial Function Kieren J. Mather, Alain Baron, and Michael J. Quon Chapter 7 Macro and Micro Vascular Disease in an Insulin Resistant - Pre-diabetic Animal Model (the JCR:LA-cp Rat) James C. Russell and Spencer D. Proctor: Chapter 8 High Sensitivity C-reactive protein (Hs-CRP) in Metabolic Syndrome Yiqing Song, Simin Liu, and JoAnn Manson Chapter 9 Insulin Signaling in Adipocytes and the Role of Inflammation Christian X. Andersson, Ann Hammarstedt, Per-Anders Jansson and Ulf Smith Chapter 10 Insulin Resistance and Dyslipidemia Tina J. Cahil, Gissette Reyes, and Henry N. Ginsberg Part III: Insulin - Secretion and Action: Underlying mechanisms of the metabolic syndrome Chapter 11 Pancreatic Islet Pathophysiology and Pathology in Obesity Anne Clark, Jenni Moffitt, Leanne van de Laar, Katherine Pinnick, Farhina Sayyed Chapter 12 Glucagon Peptides and Insulin Sensitivity Jens Juul Holst and Filip Krag Knop Chapter 13 The Relationship between the Insulin Receptor Substrates and Metabolic Disease Morris F. White Chapter 14 Insulin Resistance and Inhibitors of the Insulin Receptor Tyrosine Kinase Jack F. Youngren Chapter 15 Fat Feeding and Muscle Fat Deposition Eliciting Insulin Resistance: an update E.W. Kraegen, G.J. Cooney, J.M. Ye, and S.M. Furler: Chapter 16 Alternations in Atypical Protein Kinase-C (APK-C) Activation in Insulin Resistance Syndrome Robert V. Faresse Chapter 17 The Liver's Role in Insulin Action and Resistance

Inhaltsverzeichnis

Part I: Epidemiology and Clinical Treatment: Issues in defining and treating the metabolic syndrome Chapter 1 Metabolic Syndrome: to be or not to be? Gerald M. Reaven Chapter 2 The Role of Obesity in Insulin Resistance: Epidemiological and metabolic aspects James B. Meigs Chapter 3 Treatment of the Metabolic Syndrome with Weight Loss, Exercise, Hormones, and Surgery George A. Bray Chapter 4 Insulin Resistance, Metabolic Syndrome, and Cardiovascular Disease: an epidemiological perspective Earl Ford and Simin Liu Chapter 5 The Sympatho-Adrenal System in Metabolic Syndrome Lewis Landsberg Part II: Endothelial Function, Inflammation, and Dyslipidemia Chapter 6 Insulin Action and Endothelial Function Kieren J. Mather, Alain Baron, and Michael J. Quon Chapter 7 Macro and Micro Vascular Disease in an Insulin Resistant - Pre-diabetic Animal Model (the JCR:LA-cp Rat) James C. Russell and Spencer D. Proctor: Chapter 8 High Sensitivity C-reactive protein (Hs-CRP) in Metabolic Syndrome Yiqing Song, Simin Liu, and JoAnn Manson Chapter 9 Insulin Signaling in Adipocytes and the Role of Inflammation Christian X. Andersson, Ann Hammarstedt, Per-Anders Jansson and Ulf Smith Chapter 10 Insulin Resistance and Dyslipidemia Tina J. Cahil, Gissette Reyes, and Henry N. Ginsberg Part III: Insulin a¿'' Secretion and Action: Underlying mechanisms of the metabolic syndrome Chapter 11 Pancreatic Islet Pathophysiology and Pathology in Obesity Anne Clark, Jenni Moffitt, Leanne van de Laar, Katherine Pinnick, Farhina Sayyed Chapter 12 Glucagon Peptides and Insulin Sensitivity Jens Juul Holst and Filip Krag Knop Chapter 13 The Relationship between the Insulin Receptor Substrates and Metabolic Disease Morris F. White Chapter 14 Insulin Resistance and Inhibitors of the Insulin Receptor Tyrosine Kinase Jack F. Youngren Chapter 15 Fat Feeding and Muscle Fat Deposition Eliciting Insulin Resistance: an update E.W. Kraegen, G.J. Cooney, J.M. Ye, and S.M. Furler: Chapter 16 Alternations in Atypical Protein Kinase-C (APK-C) Activation in Insulin Resistance Syndrome Robert V. Faresse Chapter 17 The Liver¿s Role in Insulin Action and Resistance

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