Targeting Enzymes for Pharmaceutical Development

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128,39 

Methods and Protocols, Methods in Molecular Biology 2089

ISBN: 1071601652
ISBN 13: 9781071601655
Herausgeber: Nikolaos E Labrou
Verlag: Springer Verlag GmbH
Umfang: xi, 290 S., 42 s/w Illustr., 71 farbige Illustr., 290 p. 113 illus., 71 illus. in color.
Erscheinungsdatum: 27.11.2020
Auflage: 1/2020
Produktform: Kartoniert
Einband: Kartoniert

This volume explores detailed methods and experimental protocols evaluating the effect of a compound or a mixture of compounds on the action of enzymes that are significant targets in pharmaceuticals. Consisting of three sections, the book delves into recent biocomputing and bioinformatics protocols, state-of-the art modern biophysical, electrophoretic, and chromatographic methods and high-throughput screening approaches, as well as detailed protocols and examples of the inhibition analysis and evaluation of selected enzymes. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Targeting Enzymes for Pharmaceutical Development: Methods and Protocols serves as a vital reference for academics and industry professionals working on expanding our understanding of the wide range of important enzyme targets. The chapter „Enzyme-Ligand Interaction Monitored by Synchrotron Radiation Circular Dichroism“ is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

Artikelnummer: 133482 Kategorie:

Beschreibung

This volume explores detailed methods and experimental protocols evaluating the effect of a compound or a mixture of compounds on the action of enzymes that are significant targets in pharmaceuticals. Consisting of three sections, the book delves into recent biocomputing and bioinformatics protocols, state-of-the art modern biophysical, electrophoretic, and chromatographic methods and high-throughput screening approaches, as well as detailed protocols and examples of the inhibition analysis and evaluation of selected enzymes. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.  Authoritative and cutting-edge, Targeting Enzymes for Pharmaceutical Development: Methods and Protocols serves as a vital reference for academics and industry professionals working on expanding our understanding of the wide range of important enzyme targets.

Herstellerkennzeichnung:


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E-Mail: juergen.hartmann@springer.com

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