Peristence of foot-and-mouth disease virus in cattle

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Foot-and-mouth disease virus persistence

ISBN: 3659229431
ISBN 13: 9783659229435
Autor: Kumar, Naveen
Verlag: LAP Lambert Academic Publishing
Umfang: 132 S.
Erscheinungsdatum: 17.09.2012
Auflage: 1/2012
Format: 0.7 x 22 x 15
Gewicht: 213 g
Produktform: Kartoniert
Einband: KT
Artikelnummer: 4019426 Kategorie:

Beschreibung

In the present study baculovirus expressed non-structural-protein (NSP) 3A of FMD virus (FMDV) was used to develop an indirect ELISA for differentiation of FMDV infected and vaccinated animals (DIVA). Using this test, field sera (from Haryana, India) were tested where a significant reduction (P32). In 1st HtCE (AIraq22 vaccine/AIran96 challege virus), the vaccine offered good protection (PD50>6) but the vice versa of vaccine and challenge virus in 2nd HtCE could not offer protection (PD50<2). High potency vaccine was found to reduce the carrier state in HoCE but in HtCEs, inspite of giving good protection in certain cases, it could not prevent the development of carrier state.

Autorenporträt

Dr. Naveen Kumar was born in Dhakla (Jhajjar), Haryana of India. He studied in CCS Haryana Agricultural University, Hisar (India) where he successfully completed two degrees: a M.Sc. in Biotechnology & Molecular Biology in 2010, and Ph.D. in Molecular Biology and Biotechnology, which was achieved in 2014.

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