Toxicity and Drug Testing

Lieferzeit: Lieferbar innerhalb 14 Tagen

175,00 

ISBN: 9535100041
ISBN 13: 9789535100041
Herausgeber: Bill Acree
Verlag: IntechOpen
Umfang: 530 S., 50 farbige Illustr.
Erscheinungsdatum: 10.02.2012
Auflage: 1/2012
Format: 4.1 x 26.6 x 18.5
Gewicht: 1349 g
Produktform: Gebunden/Hardback
Einband: Gebunden
Artikelnummer: 7802854 Kategorie:

Beschreibung

Modern drug design and testing involves experimental in vivo and in vitro measurement of the drug candidate's ADMET (adsorption, distribution, metabolism, elimination and toxicity) properties in the early stages of drug discovery. Only a small percentage of the proposed drug candidates receive government approval and reach the market place. Unfavorable pharmacokinetic properties, poor bioavailability and efficacy, low solubility, adverse side effects and toxicity concerns account for many of the drug failures encountered in the pharmaceutical industry. Authors from several countries have contributed chapters detailing regulatory policies, pharmaceutical concerns and clinical practices in their respective countries with the expectation that the open exchange of scientific results and ideas presented in this book will lead to improved pharmaceutical products.

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