The new heteroaryl compounds having 5-HT1A / 5-HT2A affinity

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Design, synthesis & evaluation of some new heteroaryl compounds having 5-HT1A/5-HT2A affinity and anticonvulsant activity

ISBN: 3659694886
ISBN 13: 9783659694882
Autor: Dhanawat, Minakshi/Sharma, Gaurav Kumar/Shrivastava, Sushant Kumar
Verlag: LAP LAMBERT Academic Publishing
Umfang: 140 S.
Erscheinungsdatum: 08.05.2015
Auflage: 1/2015
Format: 0.9 x 22 x 15
Gewicht: 227 g
Produktform: Kartoniert
Einband: KT
Artikelnummer: 8168652 Kategorie:

Beschreibung

The ultimate goal of the experiments conducted in the realm of this work was to design, synthesize, characterize some novel heterocyclic compounds comprising of 4-arylpiperazine/ aniline moiety linked to a terminal cyclic amide through a spacer followed by their biological evaluation and molecular modeling studies as anti-convulsants and evaluation of their interactions with 5-HT1A and 5-HT2A receptor subtypes as agonist/antagonist through validated in vivo behavioral models.

Autorenporträt

Dr.Meenakshi dhanawat,PhD(Pharmaceutical Chemistry),Department of Pharmaceutics,IIT-BHU Varanasi,U.P.,Assistant prof. And HODDepartment of Pharmacy ,Mewar University, (Gangrar)Chittorgarh, Rajasthan

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