Standardization of Nothapodytes foetida

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39,90 

ISBN: 3659377023
ISBN 13: 9783659377020
Autor: Sharma, Ajay/Mhase, Archana G/Gurav, Arun M
Verlag: LAP LAMBERT Academic Publishing
Umfang: 88 S.
Erscheinungsdatum: 10.06.2015
Auflage: 1/2015
Format: 0.6 x 22 x 15
Gewicht: 149 g
Produktform: Kartoniert
Einband: Kartoniert
Artikelnummer: 8272873 Kategorie:

Beschreibung

In the past few decades there has been an exponential growth in the field of herbal medicine due to its natural origin, minor side effects, and are considered to be safe. Commercialization of the manufacture of herbal medicines to meet this increasing demand has resulted in decline their quality, primarily due to a lack of adequate regulations concerning to this sector of medicine. The need of the hour is to evolve a systematic approach and to develop well-designed methodologies for the standardization of herbal raw drugs and their formulations. The standardization of the herbal drugs is essential for assuring the therapeutic effectiveness of the herbal drugs. Nothapodytes foetida (Wight) Sleumer (Family Icacinaceae) is an endangered medicinal plant that contains pyrrolo quinoline alkaloid, camptothecin (CPT). The cellular target of CPT is DNA topoisomerase I, an enzyme involved in DNA replication. Camptothecin has been shown to be effective in the complete remission of lung, breast, uterine and cervical cancer. However, no scientific standards or pharmacognostical and phytochemical parameters are yet available to ascertain the identity and to determine the quality of N. foetida.

Autorenporträt

Dr. Ajay Sharma presently working as Director In-Charge, ShriRam College of Pharmacy, Banmore, India. He did his PhD in 2011 at Bharati Vidyapeeth University, Pune, India. His research interest includes extraction, isolation and purification of secondary metabolites and their pharmacological screening for various activities like inflammation.

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