Molecular Toxicology Protocols

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149,79 

Methods in Molecular Biology 1105

ISBN: 149395654X
ISBN 13: 9781493956548
Herausgeber: Phouthone Keohavong/Stephen G Grant
Verlag: Humana Press
Umfang: xv, 646 S., 72 s/w Illustr., 29 farbige Illustr., 646 p. 101 illus., 29 illus. in color.
Erscheinungsdatum: 03.09.2016
Auflage: 2/2014
Produktform: Kartoniert
Einband: Kartoniert

This book details techniques for analyzing genotoxic exposure and the resulting biological effects, including intermediate biomarkers such as DNA and chromosomal damage, mutations in reporter and oncogenes, and the earliest possible detection of cancer.

Artikelnummer: 9808686 Kategorie:

Beschreibung

Molecular Toxicology Protocols, Second Edition aims to bring together a series of articles describing validated methods to elucidate specific molecular aspects of toxicology, the emphasis being on the application of molecular methods to genetic toxicology. The volume is divided into ten parts, roughly corresponding to the spectrum of biomarkers intermediate between exposure and disease outcomes as proposed in molecular epidemiology models. Subjects of these new chapters range from preparation of fluid specimens for analysis of cellular inflammatory responses to genotoxic insults to sensitive methods for proteomic analysis and aberrant DNA methylation patterns. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls.Authoritative and easily accessible, Molecular Toxicology Protocols, Second Edition addresses not only the needs of molecular biologists and toxicologists, but also those of individuals interested in applying molecular methods to clinical applications, such as geneticists, pathologists, biochemists, and epidemiologists. 

Herstellerkennzeichnung:


Humana Press in Springer Science + Business Media
Heidelberger Platz 3
14197 Berlin
DE

E-Mail: juergen.hartmann@springer.com

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