Microemulsions for Topical Administration

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Preparation and Evaluation of 5 Flurouracil Microeumlsion for Topical Administration

ISBN: 3639666259
ISBN 13: 9783639666250
Autor: Sharma, Harish/Sahu, Gyanesh/Kaur, Chanchal Deep
Verlag: Scholars‘ Press
Umfang: 76 S.
Erscheinungsdatum: 04.11.2014
Auflage: 1/2014
Format: 0.6 x 22 x 15
Gewicht: 131 g
Produktform: Kartoniert
Einband: Kartoniert
Artikelnummer: 7452491 Kategorie:

Beschreibung

In the recent years microemulsions have attracted a great deal of attention not because of their importance in industrial application but also their intrinsic interest. Microemulsions are colloidal dispersions composed of an oil phase, aqueous phase, surfactant and cosurfactant at appropriate ratios. Microemulsions are an attractive technology platform for the pharmaceutical formulators as it has excellent solubilisation properties, transparency and the relatively simple formulation process.Microemulsions are an attractive technology platform for the pharmaceutical formulators as it has excellent transparency and the relatively simple formulation process. The role of microemulsion systems is of paramount importance in providing novel solutions to overcome the problems of poor aqueous solubility of highly lipophilic drug compounds and provide high, more consistent and reproducible bioavailability. The 5-fluorouracil topical microemulsions were formulated and the different compositions of components were obtained by constructing pseudoternary phase diagrams. Their concentrations were optimized after the evaluation of their effect on permeation of drug.

Autorenporträt

Mr. Harish Sharma is from SSGI- Faculty of Pharmaceutical Sciences, Bhilai, India and Mr. Gyanesh Sahu and Dr. Chanchal Deep Kaur are from Shri Rawatpura Sarkar Institute of Pharmacy, Kumhari, India. Their areas of research extends from topical drug delivery, NDDS, drug targeting, autoimmune disorders,skin ailments to herbal drug development.

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