Development and optimization of novel controlled-release micropellets

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49,90 

ISBN: 3330085576
ISBN 13: 9783330085572
Autor: Mishra, Dinesh Kumar/Dhote, Vinod Kumar
Verlag: LAP LAMBERT Academic Publishing
Umfang: 104 S.
Erscheinungsdatum: 06.06.2017
Auflage: 1/2017
Format: 0.7 x 22 x 15
Gewicht: 173 g
Produktform: Kartoniert
Einband: KT
Artikelnummer: 2469738 Kategorie:

Beschreibung

A relatively more recent approach that has come into existence is the one that combines the features of both controlled release tablets and modified release capsules in one dosage form known as multiple unit dosage form e.g. Micropellets. Past few years multipariculate drug delivery system has emerged as a tool for the delivery of the drugs. These forms play major role in the design of solid dosage form because of their characteristic properties and flexibility found in their manufacturing.Use of micropellets as a vehicle in multipariculate drug delivery system has received significant attention. Multiparticulate dosage forms are pharmaceutical formulations in which the active substance is present as a number of small independent subunits with diameter of 0.05-2.00 mm. In case of oral products micropellets solve difficult taste-masking problems while maintaining a high degree of bioavailability due to smaller in size (10 - 600 µm). Due to their unique properties and flexibility of manufacturing involved, micropellets are expected to continue to play a major role in the fabrication of solid dosage forms.

Autorenporträt

Dr. Dinesh Kumar Mishra has nearly 15 years of research and teaching experience at both undergraduate and post graduate levels. He is a leading scientist and academician and having 45 research publications to his credit published in international and national journals. Mr. Vinod Kumar Dhote has nearly 6 years of research and teaching experience.

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