Beschreibung
Nicorandil is Anti-anginal drug. There are several methods like HPLC, LC-MS, Ultraviolet Spectroscopy etc. are available for the estimation of Nicorandil in biological fluids and pharmaceutical dosage form.we could not trace Single HPLC Method with short Retention Time (RT). So to develop and validate a HPLC method for the estimation of Nicorandil in Pharmaceutical with the retention time around 5 min. HPLC method for estimation of Nicorandil in its dosage form was developed. The developed HPLC method was validated for specificity, linearity and range, accuracy, method and intermediate precision, robustness, system suitability and applied to pharmaceutical formulation and the %Assay of Nicorandil Tablets was found to be in the range of 98-102%. For developing HPLC technique for analysis of Nicorandil tablet. Numbers of trials were taken for selection of column, mobile phase. The developed method was validated as per ICH guideline. The advantages of chromatographic techniques were higher accuracy, small sample size and less consuming, however it requires costly HPLC grade solvents and availability of HPLC instrument. This method can be successfully applied for the estimation.
Autorenporträt
My self quality fellow, believing in quality and ever focus in innovation, improvisation & creativity. Quality is never an accident it is always the results of high intention, sincere effort, intelligent direction and skillful execution, it represents the wise choice of many alternatives. "Quality Can Earn Money"
Herstellerkennzeichnung:
BoD - Books on Demand
In de Tarpen 42
22848 Norderstedt
DE
E-Mail: info@bod.de
