Beschreibung
This book covers all aspects of oxygen delivery to tissue, including blood flow and its regulation as well as oxygen metabolism. Special attention will be paid to methods of oxygen measurement in living tissue and application of these technologies to understanding physiological and biochemical basis for pathology related to tissue oxygenation. This book is multidisciplinary and designed to bring together experts and students from a range of research fields including biochemical engineering, physiology, microcirculation, and hematology.
Autorenporträt
InhaltsangabePart 1 - Near Infrared Spectroscopy Chapter 1 The Western Reserve, Edward Morley and Oxygen Chapter 2 Analysis of the Changes in the Oxidation of Brain Tissue Cytochrome c Oxidase in Traumatic Brain Injury Patients during Hypercapnoea: A Broadband NIRS Study Chapter 3 Effects of Assuming Constant Optical Scattering on Haemoglobin Concentration Measurements using NIRS during a Valsalva Manoeuvre Chapter 4 Speech Therapy Changes Blood Circulation and Oxygenation in the Brain and Muscle. A Near-Infrared Spectrophotometry Study Part 2 Oxygen Sensors and Measurement Chapter 5 Evaluation of Lithium Naphthalocyanine (LiNc) Microcrystals for Biological EPR Oximetry Chapter 6 Challenges to Intestinal pO2 Measurement Using EPR Chapter 7 Quantification of Systemic Interference in Optical Topography Data during Frontal Lobe and Motor Cortex Activation: An Independent Component Analysis Chapter 8 Measuring Oxygen in Living Tissue: Intravascular, Interstitial and "Tissue" Oxygen Measurements Chapter 9 Cerebral Oxygenation of the Cortex and Striatum following Normobaric Hyperoxia and Mild Hypoxia in Rats by EPR Oximetry Using Multi-Probe Implantable Resonators Chapter 10 31PMRS Studies of Melanoma Xenograft Metastatic Potential Chapter 11 Modulation of Tumor Hypoxia by Topical Formulations with Vasodilators for Enhancing Therapy Part 3 Blood and Blood Substitutes Chapter 12 MP4, A Vasodilatory PEGylated Hemoglobin Chapter 13 Zymogen Protein C to Prevent Clotting Without Bleeding During Invasive Medical Procedures Part 4 Tumor Biology Chapter 14 Oxygenation Status of Urogenital Tumors Chapter 15 Tumor pO2 as a Surrogate Marker to Identify Therapeutic Window during Metronomic Chemotherapy of 9L Gliomas Chapter 16 Hypoxiainduced Extracellular Acidosis Increases pglycoprotein activity and chemoresistance in tumors in vivo via p38 signaling pathway Chapter 17 Evidence Against a Major Role for TKTL-1 in Hypoxic and Normoxic Cancer Cells Chapter 18 NMR Metabolic and Physiological Markers of Therapeutic R
