Beschreibung
This book is unique due to its collective approach to the key aspects of the interdependency between three entities: oxidative stress, tobacco smoke and carcinogenesis, operating in a cause-effect sequence, in a concise and to the point manner. This book will prove to be a helpful companion to the internist, the oncologist and the research scientist in molecular biology as well as a work of reference for the general practitioner and physician interested in cancer research.
Inhaltsverzeichnis
Chapter 1: Oxygen and Nitrogen free radicals Chapter 2: Oxidative stress Chapter 3: Oxidative damage of genome DNA: repair mechanisms Chapter 4: Mitochondria: structure, function and relationship with carcinogenesis Chapter 5: Oxidative activation of transcription factor pathways by cigarette smoke oxidants Chapter 6: Cell protection mechanisms from oxidation Chapter 7: Role of DNA adducts in carcinogenesis Chapter 8: Transmolecular reactions of genetic toxicity: alkylation and methylation of DNA Chapter 9: Toxicity and carcinogenicity of hydrocarbons Chapter 10: Toxicity and carcinogenicity of the aromatic hydrocarbons Chapter 11: Toxicity and carcinogenicity of aldehydes Chapter 12: Toxicity and carcinogenicity of the nitriles Chapter 13: Toxicity and carcinogenicity of the eterocyclic organic compounds Chapter 14: Toxicity and carcinogenicity of metals Chapter 15:Oxidative profile of cigarette smoke and lung cancer Chapter 16: Smoking and lung cancer
