Beschreibung
InhaltsangabePart I: The G Protein-Coupled Receptor in the Genome 1. In Silico Identification of Novel G Protein-Coupled Receptors Matthew N. Davies, David E. Gloriam, and Darren R. Flower 2. Alternative Pre-mRNA Splicing of G Protein-Coupled Receptors Ying-Xian Pan, Steven Grinnell, and Gavril W. Pasternak 3. Detecting Polymorphisms in G Protein-Coupled Receptor Genes Dmitri Proudnikov, Vadim Yuferov, and Mary Jeanne Kreek 4. Regulation of the Transcription of G Protein-Coupled Receptor Genes Cheol Kyu Hwang, Ping-Yee Law, Li-Na Wei, and Horace H. Loh 5. Deciphering the Evolution of G Protein-Coupled Receptors in Vertebrates Craig W. Stevens Part II: The Trafficking of G Protein-Coupled Receptors 6. A New Approach to Visualize Endogenously Expressed G Protein-Coupled Receptors in Tissues and Living Cells Brigitte L Kieffer and Grégory Scherrer 7. Post-Translational Regulation of G Protein-Coupled Receptors Yu Qiu and Ping-Yee Law 8. Discovering G Protein-Coupled Receptor Motifs Mediating Export from the Endoplasmic Reticulum Chunmin Dong and Guangyu Wu 9. Identifying G Protein-Coupled Receptor Escorts, Chaperones, and Intracellular Tethers Regulating Receptor Density at the Cell Surface Stefano Marullo, Liliana Pardo Lopez, and Lamia Achour 10. A Novel Method for Determining the Kinetics of G Protein-Coupled Receptor Plasma Membrane Expression Gregory W. Sawyer Part III: The G Protein-Coupled Receptor on the Membrane 11. Characterizing the Pharmacology of G Protein-Coupled Receptors in Transfected Cell Lines Kathryn A. Seely and Paul L. Prather 12. Novel Assay Technologies for the Discovery of G Protein-Coupled Receptor Drugs Elisa Alvarez-Curto, Richard J. Ward, and Graeme Milligan 13. Discovering Cell-Type-Specific Patterns of G Protein-Coupled Receptor Phosphorylation Kok Choi Kong, Andrew B. Tobin, and Adrian J. Butcher 14. Quantifying Allosteric Modulation of G Protein-Coupled Receptors Frederick J. Ehlert and Hinako Suga 15. Experimental Designs for the Study of Receptor-Receptor Interactions Dennis Paul Part IV: The Regulation of G Protein-Coupled Receptors 16. Elucidating Agonist-Selective Mechanisms of G Protein-Coupled Receptor Desensitization Chris P. Bailey and Eamonn Kelly 17. Detecting the Role of Arrestins in G-Protein Coupled Receptor Regulation Laura M. Bohn and Patricia H. McDonald 18. Characterizing Molecular Mobility and Membrane Interactions of G Protein-Coupled Receptors Vladana Vukojevic, Yu Ming, and Lars Terenius 19. Using RNA Interference to Downregulate G Protein-Coupled Receptors Philippe Sarret, Louis Doré-Savard, Pascal Tétreault, Valérie Bégin-Lavallée, Marc-André Dansereau, and Nicolas Beaudet 20. Upregulating G Protein-Coupled Receptors with Receptor Antagonists Ellen M. Unterwald
Inhaltsverzeichnis
Part I: The G Protein-Coupled Receptor in the Genome 1. In Silico Identification of Novel G Protein-Coupled Receptors Matthew N. Davies, David E. Gloriam, and Darren R. Flower 2. Alternative Pre-mRNA Splicing of G Protein-Coupled Receptors Ying-Xian Pan, Steven Grinnell, and Gavril W. Pasternak 3. Detecting Polymorphisms in G Protein-Coupled Receptor Genes Dmitri Proudnikov, Vadim Yuferov, and Mary Jeanne Kreek 4. Regulation of the Transcription of G Protein-Coupled Receptor Genes Cheol Kyu Hwang, Ping-Yee Law, Li-Na Wei, and Horace H. Loh 5. Deciphering the Evolution of G Protein-Coupled Receptors in Vertebrates Craig W. Stevens Part II: The Trafficking of G Protein-Coupled Receptors 6. A New Approach to Visualize Endogenously Expressed G Protein-Coupled Receptors in Tissues and Living Cells Brigitte L Kieffer and Gregory Scherrer 7. Post-Translational Regulation of G Protein-Coupled Receptors Yu Qiu and Ping-Yee Law 8. Discovering G Protein-Coupled Receptor Motifs Mediating Export from the Endoplasmic Reticulum Chunmin Dong and Guangyu Wu 9. Identifying G Protein-Coupled Receptor Escorts, Chaperones, and Intracellular Tethers Regulating Receptor Density at the Cell Surface Stefano Marullo, Liliana Pardo Lopez, and Lamia Achour 10. A Novel Method for Determining the Kinetics of G Protein-Coupled Receptor Plasma Membrane Expression Gregory W. Sawyer Part III: The G Protein-Coupled Receptor on the Membrane 11. Characterizing the Pharmacology of G Protein-Coupled Receptors in Transfected Cell Lines Kathryn A. Seely and Paul L. Prather 12. Novel Assay Technologies for the Discovery of G Protein-Coupled Receptor Drugs Elisa Alvarez-Curto, Richard J. Ward, and Graeme Milligan 13. Discovering Cell-Type-Specific Patterns of G Protein-Coupled Receptor Phosphorylation Kok Choi Kong, Andrew B. Tobin, and Adrian J. Butcher 14. Quantifying Allosteric Modulation of G Protein-Coupled Receptors Frederick J. Ehlert and Hinako Suga 15. Experimental Designs for the Study of Receptor-Receptor Interactions Dennis Paul Part IV: The Regulation of G Protein-Coupled Receptors 16. Elucidating Agonist-Selective Mechanisms of G Protein-Coupled Receptor Desensitization Chris P. Bailey and Eamonn Kelly 17. Detecting the Role of Arrestins in G-Protein Coupled Receptor Regulation Laura M. Bohn and Patricia H. McDonald 18. Characterizing Molecular Mobility and Membrane Interactions of G Protein-Coupled Receptors Vladana Vukojevic, Yu Ming, and Lars Terenius 19. Using RNA Interference to Downregulate G Protein-Coupled Receptors Philippe Sarret, Louis Dore-Savard, Pascal Tetreault, Valerie Begin-Lavallee, Marc-Andre Dansereau, and Nicolas Beaudet 20. Upregulating G Protein-Coupled Receptors with Receptor Antagonists Ellen M. Unterwald
