Leucine-Rich Repeat Kinase 2 (LRRK2)

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160,49 

Advances in Neurobiology 14

ISBN: 331949967X
ISBN 13: 9783319499673
Herausgeber: Hardy J Rideout
Verlag: Springer Verlag GmbH
Umfang: xvii, 271 S., 10 s/w Illustr., 17 farbige Illustr., 271 p. 27 illus., 17 illus. in color.
Erscheinungsdatum: 04.04.2017
Auflage: 1/2017
Produktform: Gebunden/Hardback
Einband: Gebunden

This is the first book to assemble the leading researchers in the field of LRRK2 biology and neurology and provide a snapshot of the current state of knowledge, encompassing all major aspects of its function and dysfunction. The contributors are experts in cell biology and physiology, neurobiology, and medicinal chemistry, bringing a multidisciplinary perspective on the gene and its role in disease. The book covers the identification of LRRK2 as a major contributor to the pathogenesis of Parkinson’s Disease. It also discusses the current state of the field after a decade of research, putative normal physiological roles of LRRK2, and the various pathways that have been identified in the search for the mechanism(s) of its induction of neurodegeneration.

Artikelnummer: 125633 Kategorie:

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Springer Verlag GmbH
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69121 Heidelberg
DE

E-Mail: juergen.hartmann@springer.com

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