Advances in Biology and Therapy of Multiple Myeloma

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Volume 2: Translational and Clinical Research

ISBN: 1461452597
ISBN 13: 9781461452591
Herausgeber: Nikhil C Munshi/Kenneth C Anderson
Verlag: Springer Verlag GmbH
Umfang: x, 290 S.
Erscheinungsdatum: 06.12.2012
Auflage: 1/2013
Produktform: Gebunden/Hardback
Einband: GEB

Despite the advances in conventional, and novel agent and high dose chemotherapy, multiple myeloma remains incurable. In order to overcome resistance to current therapies and improve patient outcome, novel biologically-based treatment approaches are being developed. Current translational research in multiple myeloma focusing on the development of molecularly-based novel targeted single-agent and combination therapies has great promise to achieve high frequency and durable responses in the majority of patients. This volume will focus on biology of multiple myeloma, especially on oncogenomic changes, cell signaling pathways and intermediate molecules that are being investigated for development of novel therapies. The book will present newer developments, providing an emphasis on basic science, as well as its significant clinical impact.

Artikelnummer: 3861280 Kategorie:

Beschreibung

InhaltsangabeT cell responses in myeloma.- Novel antigenic targets for immunotherapy in myeloma.- Antibody-based therapies in Multiple Myeloma.- Defining multiple myeloma as a target for DNA gene fusion vaccines.- Harnessing allogeneic immunity for anti-myeloma response.- Dendritic cell and peptide-based vaccination in myeloma.- New Proteasome inhibitors.- Newer Imids.- New agents in myeloma.- Early Combination Studies in MM.- The effect of novel antimyeloma agents on bone metabolism.- Index.

Autorenporträt

InhaltsangabeT cell responses in myeloma.- Novel antigenic targets for immunotherapy in myeloma.- Antibody-based therapies in Multiple Myeloma.- Defining multiple myeloma as a target for DNA gene fusion vaccines.- Harnessing allogeneic immunity for anti-myeloma response.- Dendritic cell and peptide-based vaccination in myeloma.- New Proteasome inhibitors.- Newer Imids.- New agents in myeloma.- Early Combination Studies in MM.- The effect of novel antimyeloma agents on bone metabolism.- Index.

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