Multiple Myeloma

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Recent Results in Cancer Research 183

ISBN: 3540857710
ISBN 13: 9783540857716
Herausgeber: Thomas Moehler/Hartmut Goldschmidt
Verlag: Springer Verlag GmbH
Umfang: xxiv, 340 S., 100 s/w Illustr.
Erscheinungsdatum: 22.04.2011
Auflage: 1/2011
Produktform: Gebunden/Hardback
Einband: GEB

Multiple myeloma is currently still an incurable disease, but during the past decade knowledge of its molecular pathogenesis has increased rapidly. This has led to remarkable progress in both diagnosis and therapy. In particular, the approval of novel and first-in-class drugs such as thalidomide, bortezomib, and lenalidomide means that multiple myeloma now stands at the forefront of advances in oncology drug development. This book, written by internationally acknowledged experts, covers a wide range of topics relating to multiple myeloma, including history, epidemiology, pathophysiology, clinical features, staging, and prognostic systems. The principal focus, however, is on therapy, with detailed information on the various promising treatment options which give hope that this cancer will be transformed into a chronic disease or even become curable. Individualized therapy and the variety of supportive treatment options, as described in this volume, will help in achieving this goal, as well as in reducing adverse events and improving quality of life.

Artikelnummer: 1291263 Kategorie:

Beschreibung

InhaltsangabeHistory and epidemiology.- Pathophysiology: Molecular biology of plasma cell disorders. Alterations in microenvironment.- Clinical Features: Imaging. Integrated innovative approach for diagnosis and staging.- Therapy: High-dose chemotherapy and ABSCT.- Allogeneic transplantation. Novel Drugs.- Immunotherapeutic approaches.- First-line treatment and maintenance.- Relapse.- Radiotherapy.- Kyphoplasty.- Supportive Therapy.- Appendix: Staging and prognosis systems.

Inhaltsverzeichnis

History and epidemiology.- Pathophysiology: Molecular biology of plasma cell disorders. Alterations in microenvironment.- Clinical Features: Imaging. Integrated innovative approach for diagnosis and staging.- Therapy: High-dose chemotherapy and ABSCT.- Allogeneic transplantation. Novel Drugs.- Immunotherapeutic approaches.- First-line treatment and maintenance.- Relapse.- Radiotherapy.- Kyphoplasty.- Supportive Therapy.- Appendix: Staging and prognosis systems.

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