Formulation And Evaluation Of Sustained Release Microspheres

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Development Of Microsphere

ISBN: 6202526823
ISBN 13: 9786202526821
Autor: Jagannath, Shid Shubhangi/Magdum, Chandrakant
Verlag: LAP LAMBERT Academic Publishing
Umfang: 92 S.
Erscheinungsdatum: 18.05.2020
Auflage: 1/2020
Format: 0.7 x 22 x 15
Gewicht: 155 g
Produktform: Kartoniert
Einband: Kartoniert
Artikelnummer: 9311223 Kategorie:

Beschreibung

Microspheres of Meclizine were prepared using the non-aqueous emulsification solvent evaporation method. The impact of different factors such type of eudragit polymer as matrix polymer. The morphology of microspheres was studied using optical and scanning electron microscopy and it was observed that microspheres had a spherical shape and smooth surface. The percentage yield of microspheres of all formulation was in the range of 82.5 % to 96.4 %. The drug content determination showed that even if the polymer composition was changed the solvent evaporation process was highly efficient to give microspheres having maximum drug loading. In conclusion, the prolonged sustained release time and enhanced stability resulting from the meclizine microspheres might make contribution to its use.

Autorenporträt

Shid Shubhangi Jagannath has completed B.Pharmacy from Rajarambapu College of Pharmacy,Kasegaon and M.Pharmacy in the same college. Currently  is working as an assistant professor.  

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