Beschreibung
This volume contains the papers presented at cluded are the concluding remarks made by the the Sixth International Symposium on Cerebral chairman of each session. The last session con Blood Flow held in Philadelphia on June 6-9, tains discussions of several topics which were felt to be of sufficient importance and interest to 1973. Since the first meeting on cerebral blood flow, held in Lund in 1964, the number of par warrant extended consideration. These con ticipants in these symposia has steadily increased cerned the questions of neurogenic control of until at this meeting it was necessary to conduct the cerebral circulation, the role of failure of simultaneous sessions. The interest and effort reperfusion in cerebral ischemia, and a discus sion of invasive and noninvasive methods of directed toward problems concerned with cere bral circulation and metabolism, as well as the CBF determination. Owing to the large number increasing sophistication applied to these prob of papers included in this book and the interests lems, are amply demonstrated in this book. of rapid publication, it was not possible to in A wide variety of topics was discussed at the clude the discussions of each paper. The orga symposium with major emphasis on the basic nizers regret the necessity of this decision but aspects of the control of cerebral circulation and wish to thank the many participants who con metabolism.
Autorenporträt
InhaltsangabeSession 1 Autoregulation.- The Lower and Upper Limits for Autoregulation of Cerebral Blood Flow.- Acute Arterial Hypertension and the Blood-Brain Barrier: An Experimental Study in Dogs.- Effects of Local Increases of Venous Pressure on Canine Cerebral Hemodynamics.- The Effect of Lowered Cardiac Output on Cerebral Blood Flow.- Autoregulation of Cerebral Blood Flow During Controlled Hypotension.- Cerebral Blood Flow Autoregulation, Cerebrospinal Fluid Acid-Base Parameters, and Profound Hypotension Induced by Sodium Nitroprusside and Deep Halothane Anesthesia.- Correlation of Regional Cerebral Blood Volume with PaCO2 and Arterial Blood Pressure.- Cerebral Blood Flow and Metabolism with Regard to Autoregulation in Cerebral Perfusion Pressure Experiments.- Summary of Session 1.- Session 2 Chemical Control.- The Effect of Metabolic Alkalosis on Cerebral Blood Flow in Man.- Circulation to the Brain of Rats During Acute and Prolonged Hypercapnia and Hypocapnia.- Primate Pial Arterial Pressure Responses to Changes in Inspired CO2 and Systemic Arterial Pressure.- Dual Control of Cerebral Circulation: Separate Sites of Action in Vascular Tree in Autoregulation and Chemical Control.- Interdependence of Capillary Flow and Regional Blood Flow of the Brain.- Interactions of Ionic Mechanisms in the Regulation of the Resistance of Pial Vessels.- The Effect of Local Changes in Bicarbonate and Potassium Concentration on Hypothalamic Blood Flow.- Cerebral Hemodynamics: The Effect of Hypoxia on Autoregulation and CO2 Reactivity.- Summary of Session 2.- Session 3 Focal Lesions I.- Acute Systemic Hypertension and Resultant Prolonged Focal Cerebral Ischemia.- Cerebral Edema Due to Cerebral Infarction in the Gerbil.- Development and Resolution of Edema in Experimental Cerebral Ischemia and Infarction.- Cerebral Blood Flow in the Baboon Following Carotid Ligation: Effects of Hypoxia and Hypotension.- Atraumatic Transient Focal Cerebral Ischemia in Monkeys.- Alpha Methyl p-Tyrosine and Experimental Stroke.- Energy Metabolites, Water Content, and Catecholamine Changes in a Model of Cerebral Embolic Infarction.- Regional Cerebral Metabolism in Experimental Brain Infarction.- Segmental Reactivity of Cerebral Vessels and Brain Damage.- Summary of Session 3.- Session 4 Focal Lesions II.- False Autoregulation After Cold Injury to the Cerebral Cortex.- CBF and Regional Energy Metabolism in Cold-Injury Edema Following Moderate and Severe Hypocapnia or Hypercapnia.- Quantitative Studies of Experimental Cerebral Edema.- Focal Autoregulatory Disturbances in Middle Cerebral Artery Vasospasm.- Regional Blood Flow in the Brain and in the Cervical Cord in Experimental Head Trauma.- The Experimental Production of Charcot-Bouchard Miliary Arterial Microaneurysms in Hypertensive Rabbits.- Cerebrovascular Response to Hypocapnia in Normal and Brain-Injured Dogs.- Summary of Session 4.- Session 5 Methodology I.- Discrepancies in the Results of Flow Measurements Using Different Isotopes: 85Kr, 133Xe, and 14C-Antipyrine.- The Influence of Capillary Permeability Limitations on the Measurement of Regional Cerebral Blood Flow.- Brain Concentrations of 14C-Nicotine and 14C-Antipyrine After Intravenous Injection.- Variation in Gamma Index (Dimensionless Dispersion) of Hydrogen Gas in a Single Human Brain.- Determination of Diffusion Shunt in Brain and Its Influence on Blood Flow Measurements. A Diffusion Shunt Model.- Heterogeneity of Regional Cerebral Blood Flow and Regional Distribution of Relative Weights of Gray and White Matter in Normal Subjects.- The Effect of Changes in Cerebral Blood Flow on Compartmental Weight.- Regional Cerebral Blood Flow. Evaluation of the Microsphere Technique.- Pulsatile Blood Flow Pattern in Cerebral Circulation.- Heterogeneity of Tritiated Water Uptake by the Brain.- Summary of Session 5.- Session 6 Diffuse Ischemia I.- Irreversible Brain Damage Produced by Hypoxia.- Disturbances of Cerebral Microcirculation after Cerebral Ischemia.- Postischemi
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