Programmed Necrosis

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Methods and Protocols, Methods in Molecular Biology 1857

ISBN: 1493987534
ISBN 13: 9781493987535
Herausgeber: Adrian T Ting
Verlag: Humana Press
Umfang: xi, 191 S., 30 s/w Illustr., 12 farbige Illustr., 191 p. 42 illus., 12 illus. in color.
Erscheinungsdatum: 23.08.2018
Auflage: 1/2019
Produktform: Gebunden/Hardback
Einband: GEB

This volume explores the latest techniques and approaches used to study this emerging form of cell death. The chapters in this book cover topics such as distinguishing necroptosis from apoptosis; detecting MLKL oligomerization during programmed necrosis; analyzing the RIPK3 necrosome complex; using RIPK1 kinase small molecule inhibitors in studying necroptosis; monitoring RIPK1 phosphorylation in the TNFR1 signaling complex; and assessing in vivo kidney cell death in glomerular injury. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cuttingedge and thorough, Programmed Necrosis: Methods and Protocols is a valuable resource for technicians, graduate students, postdoctoral fellows, and other scientists who are pursuing studies in this field.

Artikelnummer: 5189390 Kategorie:

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