Intrinsically Disordered Protein Analysis

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Volume 2, Methods and Experimental Tools, Methods in Molecular Biology 896

ISBN: 1493944843
ISBN 13: 9781493944842
Herausgeber: Vladimir N Uversky/A Keith Dunker
Verlag: Springer Verlag GmbH
Umfang: xiv, 454 S.
Erscheinungsdatum: 23.08.2016
Auflage: 1/2012
Produktform: Kartoniert
Einband: Kartoniert

The second volume in the series on the experimental methods used to identify IDPs and analyze their structure, this publication includes reproducible protocols for single molecule techniques and methods to assess protein size and shape, among many others.

Artikelnummer: 2875622 Kategorie:

Beschreibung

Over the past decade, there has been an explosive development of research of intrinsically disordered proteins (IDPs), which are also known as unfolded proteins. Structural biologists now recognize that the functional diversity provided by disordered regions complements the functional repertoire of ordered protein regions. In Intrinsically Disordered Protein Analysis: Methods and Experimental Tools, expert researchers explore the high abundance of IDPs in various organisms, their unique structural features, numerous functions, and crucial associations with different diseases. Volume 2 includes sections on single molecule techniques, methods to assess protein size and shape, analyzing conformational behavior, mass-spectrometry, expression and purification of IDP's. Written in the highly successful Methods in Molecular Biology series format, the chapters include the kind of detailed description and implementation advice that is crucial for getting optimal results in the laboratory.Thorough and intuitive, Intrinsically Disordered Protein Analysis: Methods and Experimental Tools helps scientists further their investigations of these fascinating and dynamic molecules.

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Springer Verlag GmbH
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69121 Heidelberg
DE

E-Mail: juergen.hartmann@springer.com

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