High-Throughput Metabolomics

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Methods and Protocols, Methods in Molecular Biology 1978

ISBN: 149399235X
ISBN 13: 9781493992355
Herausgeber: Angelo D’Alessandro
Verlag: Humana Press
Umfang: xv, 459 S., 20 s/w Illustr., 63 farbige Illustr., 459 p. 83 illus., 63 illus. in color.
Erscheinungsdatum: 23.05.2019
Auflage: 1/2019
Produktform: Gebunden/Hardback
Einband: GEB

This detailed volume focuses on recent technological, computational, and biostatistical advances in the field of high-throughput metabolomics. Chapters encompass methods, platforms, and analytical strategies for steady state measurements and metabolic flux analysis with stable isotope-labeled tracers, in biological matrices of clinical relevance and model organisms. Mass spectrometry-based or orthogonal methods are discussed, along with computational and statistical methods to address data sparsity in high-throughput metabolomics approaches. As a part of the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, High-Throughput Metabolomics: Methods and Protocols provides tools that can bring about the next generation of clinical biochemistry in a cost-effective, rigorous fashion, exponentially advancing our capacity to investigate nature while hastening the advent of personalized medicine.

Artikelnummer: 6215809 Kategorie:

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