Fundamentals of Protein Structure and Function

Lieferzeit: Lieferbar innerhalb 14 Tagen

149,79 

ISBN: 3319199196
ISBN 13: 9783319199191
Autor: Buxbaum, Engelbert
Verlag: Springer Verlag GmbH
Umfang: xvi, 521 S., 23 s/w Illustr., 223 farbige Illustr., 521 p. 246 illus., 223 illus. in color.
Erscheinungsdatum: 07.12.2015
Auflage: 2/2015
Produktform: Gebunden/Hardback
Einband: Gebunden

This book serves as an introduction to protein structure and function. Starting with their makeup from simple building blocks, called amino acids, the 3-dimensional structure of proteins is explained. This leads to a discussion of how misfolding of proteins causes diseases like cancer, various encephalopathies, or diabetes. Enzymology and modern concepts of enzyme kinetics are then introduced, taking into account the physiological, pharmacological, and medical significance of this often neglected topic. This is followed by thorough coverage of hæmoglobin and myoglobin, immunoproteins, motor proteins and movement, cell-cell interactions, molecular chaperones and chaperonins, transport of proteins to various cell compartments, and solute transport across biological membranes. Proteins in the laboratory are also covered, including a detailed description of the purification and determination of proteins, as well as their characterisation for size and shape, structure, and molecular interactions. The book emphasises the link between protein structure, physiological function, and medical significance.This book can be used for graduate and advanced undergraduate classes covering protein structure and function and as an introductory text for researchers in protein biochemistry, molecular and cell biology, chemistry, biophysics, biomedicine, and related courses.About the author:Dr. Buxbaum is a biochemist with an interest in enzymology and protein science. He has been working on the biochemistry of membrane transport proteins for nearly thirty years and has taught courses in biochemistry and biomedicine at several universities.

Artikelnummer: 8119509 Kategorie:

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