Beschreibung
This book summarizes the fast-growing and current knowledge about selenium interaction with cancer, diabetes, neuro-degeneration, heart disease, muscle disorders, HIV and several more. A special focus will be placed on in-depth knowledge about gene expression, selenoprotein biosynthesis, seleno-metabolism--as well as the molecular pathways, physiological roles, and the molecular action of selenium including interaction with other elements and vitamins or as Se-nanoparticles. The reader will receive the newest information regarding redox status and redox regulatory systems, specifically in relation to different glutathione peroxidases and thioredoxin-reductases as well as about cellular bioavailability and cytotoxicity, de-balanced immune response, inflammation or dietary aspects.
Autorenporträt
Bernhard Michalke is head of the research group "Elements and Element Speciation" and of the "Central Inorganic Analysis Division" as well as deputy director of the research unit "Analytical BioGeoChemistry" at the Helmholtz Zentrum München - German Research Center for Environmental Health. He is also a lecturer at the Institute of Analytical Chemistry and Food Chemistry of the Technical University of Graz, Austria, which is where he received his habilitation in analytical chemistry. His research interests encompass speciation projects related to environmental health, i.e. the exposure and chemical speciation of neurodegenerative elements such as manganese, iron, copper or selenium and species-related neurotoxic effects in the central nervous system. He has published more than 200 peer reviewed articles and 10 book chapters. He has been and continues to be a co-organizer of several international conferences.
Herstellerkennzeichnung:
Springer Verlag GmbH
Tiergartenstr. 17
69121 Heidelberg
DE
E-Mail: juergen.hartmann@springer.com
