Beschreibung
InhaltsangabePart I. History and Overview Pharmacogenomics: Historical Perspective and Current Status Werner Kalow Part II. Functional Analysis of Gene Variation Transfection Assays With Allele-Specific Constructs: Functional Analysis of UDP-Glucuronosyltransferase Variants Hideto Jinno, Nobumitsu Hanioka, Toshiko Tanaka-Kagawa, Yoshiro Saito, Shogo Ozawa, and Jun-ichi Sawada Snapshot of the Allele-Specific Variation in Human Gene Expression Hai Yan GenomeWide Analysis of AlleleSpecific Gene Expression Using Oligo Microarrays Maxwell P. Lee HaploChIP: An In Vivo Assay Julian Charles Knight Part III. Genotyping Techniques Aspects Influencing Genotyping Method Selection Peter Imle Denaturing High-Performance Liquid Chromatography for Mutation Detection and Genotyping Donna Lee Fackenthal, Pei Xian Chen, and Soma Das Pyrosequencing of Clinically Relevant Polymorphisms Sharon Marsh, Cristi R. King, Adam A. Garsa, and Howard L. McLeod Kinetic Fluorescence-Quenching Detection Assay for Allele Frequency Estimation Ming Xiao and Pui-Yan Kwok MatrixAssisted Laser Desorption/Ionization TimeofFlight Mass Spectrometry Matthias Wjst and Dirk van den Boom FluorescenceBased Fragment Size Analysis Peter Imle SingleNucleotide Polymorphism Genotyping in DNA Pools Ian Craig, Emma Meaburn, Lee Butcher, Linzy Hill, and Robert Plomin TaqMan Genotyping of Insertion/Deletion Polymorphisms Renato Robledo, William R. Beggs, and Patrick K. Bender Part IV. Management of Pharmacogenomic Information PharmGKB: The Pharmacogenetics and Pharmacogenomics Knowledge Base Caroline F. Thorn, Teri E. Klein, and Russ B. Altman Systems for the Management of Pharmacogenomic Information Alexander Sturn, Michael Maurer, Robert Molidor, and ZlatkoTrajanoski Index
Autorenporträt
InhaltsangabePart I. History and Overview Pharmacogenomics: Historical Perspective and Current Status Werner Kalow Part II. Functional Analysis of Gene Variation Transfection Assays With Allele-Specific Constructs: Functional Analysis of UDP-Glucuronosyltransferase Variants Hideto Jinno, Nobumitsu Hanioka, Toshiko Tanaka-Kagawa, Yoshiro Saito, Shogo Ozawa, and Jun-ichi Sawada Snapshot of the Allele-Specific Variation in Human Gene Expression Hai Yan GenomeWide Analysis of AlleleSpecific Gene Expression Using Oligo Microarrays Maxwell P. Lee HaploChIP: An In Vivo Assay Julian Charles Knight Part III. Genotyping Techniques Aspects Influencing Genotyping Method Selection Peter Imle Denaturing High-Performance Liquid Chromatography for Mutation Detection and Genotyping Donna Lee Fackenthal, Pei Xian Chen, and Soma Das Pyrosequencing of Clinically Relevant Polymorphisms Sharon Marsh, Cristi R. King, Adam A. Garsa, and Howard L. McLeod Kinetic Fluorescence-Quenching Detection Assay for Allele Frequency Estimation Ming Xiao and Pui-Yan Kwok MatrixAssisted Laser Desorption/Ionization TimeofFlight Mass Spectrometry Matthias Wjst and Dirk van den Boom FluorescenceBased Fragment Size Analysis Peter Imle SingleNucleotide Polymorphism Genotyping in DNA Pools Ian Craig, Emma Meaburn, Lee Butcher, Linzy Hill, and Robert Plomin TaqMan Genotyping of Insertion/Deletion Polymorphisms Renato Robledo, William R. Beggs, and Patrick K. Bender Part IV. Management of Pharmacogenomic Information PharmGKB: The Pharmacogenetics and Pharmacogenomics Knowledge Base Caroline F. Thorn, Teri E. Klein, and Russ B. Altman Systems for the Management of Pharmacogenomic Information Alexander Sturn, Michael Maurer, Robert Molidor, and ZlatkoTrajanoski Index
