Hot-melt Extrusion

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76,90 

Process to Novel Pharmaceutical Applications

ISBN: 3659469688
ISBN 13: 9783659469688
Autor: Maniruzzaman, Mohammed
Verlag: LAP LAMBERT Academic Publishing
Umfang: 236 S.
Erscheinungsdatum: 01.12.2013
Auflage: 1/2013
Format: 1.5 x 22 x 15
Gewicht: 369 g
Produktform: Kartoniert
Einband: Kartoniert
Artikelnummer: 5961681 Kategorie:

Beschreibung

Over the last three decades industrial adaptability has allowed hot-melt extrusion (HME) to gain wide acceptance and has already established its place in the broad spectrum of manufacturing operations and pharmaceutical research development. HME has already been demonstrated as a robust, novel technique to make solid dispersions in order to provide time controlled, modified, extended, and targeted drug delivery resulting in improved bioavailability as well as taste masking of bitter active pharmaceutical ingredients (APIs). The innumerable benefits of HME, based on a holistic perspective of the equipment, processing technologies to the materials, novel formulation design and developments, and its varied applications in oral drug delivery systems (multiple case studies on dissolution enhancements of poorly water soluble APIs and taste masking of bitter substances) are surveyed in this book.

Autorenporträt

Studied and obtained BSc Hon's with first class distinction (2009) and a PhD with distinction (RDC/12/M-3/14) (2012) in Pharm Sci from the University of Greenwich,UK. Has been awarded Vice Chancellor's Award and SoS Award for PhD performance. Working as a Research Fellow (UoG) funded by Fuji Chemical Industry Co., Ltd.,Japan.

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