Formulation of particles for pulmonary drug delivery

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Effect of particle morphology on inhalation efficiency

ISBN: 384439513X
ISBN 13: 9783844395136
Autor: Hassan, Meer Saiful/Lau, Raymond
Verlag: LAP LAMBERT Academic Publishing
Umfang: 232 S.
Erscheinungsdatum: 13.05.2011
Auflage: 1/2011
Format: 1.4 x 22 x 15
Gewicht: 364 g
Produktform: Kartoniert
Einband: KT
Artikelnummer: 1123290 Kategorie:

Beschreibung

The study focuses on the formulation of particles for pulmonary drug delivery. The effect of particle shape and morphology on inhalation efficiency has been investigated. Carrier and drug model particles are formulated with a number of different surface morphology. Flowability, aerosolization and deposition behavior of particles with similar size range are investigated through in vitro experimentations. This study successfully optimizes that pollen-shape particle with fibrous surface morphology as optimum particle shape with favorable characterizing properties.

Autorenporträt

Dr. Hassan has obtained his PhD degree from Raymond Lau's research group at School of Chemical and Biomedical Engineering, Nanyang Technological University, Singapore. His research interest involved the effect of aerosol morphology on the formulation behavior for inhalation drug delivery.

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