Produktbild: Drug Target miRNA

Drug Target miRNA

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Methods and Protocols, Methods in Molecular Biology 1517

ISBN: 1493965611
ISBN 13: 9781493965618
Herausgeber: Marco F Schmidt
Verlag: Humana Press
Umfang: xi, 319 S., 32 s/w Illustr., 62 farbige Illustr., 319 p. 94 illus., 62 illus. in color.
Erscheinungsdatum: 07.12.2016
Auflage: 1/2017
Produktform: Gebunden/Hardback
Einband: Gebunden

This volume provides a concise and technical discussion of recently developed approaches to overcome challenges in miRNA drug discovery. Drug Target miRNA: Methods and Protocols explores strategies to overcome pharmacodynamics and pharmacokinetics challenges. These strategies cover anti-sense agents targeting miRNA that are applied in advanced formulations or are chemically optimized to increase delivery; small molecule miRNA modulators to overcome anti-sense agents‘ limitations; general enhancers of miRNA maturation; and Argonaute 2 protein and its pharmacokinetic parameters. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cuttingedge and thorough, Drug Target miRNA: Methods and Protocols is a valuable resource for anyone interested in the everevolving field of miRNA drug discovery.

Artikelnummer: 9555449 Kategorie:

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