PD-L1 and Hodgkins Lymphoma

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Immunohistochemical Expression of PD-L1 and EBV in Hodgkins Lymphoma

ISBN: 6207806360
ISBN 13: 9786207806362
Autor: Abdulrahman, Mohammed
Verlag: LAP LAMBERT Academic Publishing
Umfang: 128 S.
Erscheinungsdatum: 22.06.2024
Auflage: 1/2024
Format: 0.9 x 22 x 15
Gewicht: 209 g
Produktform: Kartoniert
Einband: Kartoniert
Artikelnummer: 4094054 Kategorie:

Beschreibung

In Hodgkin Lymphoma (HL), immunohistochemical expression of programmed death ligand 1 (PD-L1) is found in 67.5% of HL cases and 35% of the tumor micro-environment. However, there is no significant association between PD-L1 expression and the presence of EBV latent membrane protein-1 (LMP-1). Only 29.6% of patients with positive PD-L1 expression also show positive EBV LMP-1. Additionally, no significant associations were identified between PD-L1 expression and HL subtype, age, and gender. On the other hand, EBV LMP-1 immunohistochemical expression is significantly associated with male gender (83.3%) and certain histological subtypes but reveals no statistically significant difference concerning the age of the patients.

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