Viruses, Genes, and Cancer

Lieferzeit: Lieferbar innerhalb 14 Tagen

171,19 

Current Topics in Microbiology and Immunology 407

ISBN: 3319618032
ISBN 13: 9783319618036
Herausgeber: Eric Hunter/Klaus Bister
Verlag: Springer Verlag GmbH
Umfang: xiii, 221 S.
Erscheinungsdatum: 06.09.2017
Auflage: 1/2017
Format: 1.9 x 24.2 x 16.1
Gewicht: 510 g
Produktform: Gebunden/Hardback
Einband: Gebunden

This volume focuses on virus-host cell interactions, cellular genes acquired or modulated by viruses, the pathological effects of these interactions, and therapeutic interventions. Several chapters specifically address the role of viruses and genes – such as oncogenes, proto-oncogenes, or tumor suppressor genes – in the etiology of human cancer. Oncogenic signaling by PI3 kinase, mTOR, Akt, or the major cancer drivers MYC and RAF, and the role of tumor suppressors like p53, are discussed in detail. The volume also explores the emerging role of noncoding RNAs such as microRNAs in tumorigenesis and cancer therapeutics, and offers new insights into the role of HIV-host interactions relevant to pathogenesis and treatment. Gathering contributions written by leading scientists in their respective fields, the volume offers a valuable resource for researchers and clinicians alike.

Artikelnummer: 2425856 Kategorie:

Beschreibung

Autorenporträt

Eric Hunter, PhD, is a Professor of Pathology and Laboratory Medicine and a Georgia Research Alliance Eminent Scholar, based in Atlanta, GA, USA Klaus Bister, PhD, is a Professor Emeritus of Biochemistry of University of Innsbruck, Austria, and a Professor Adjunct of The Scripps Research Institute, La Jolla, CA, USA  

Herstellerkennzeichnung:


Springer Verlag GmbH
Tiergartenstr. 17
69121 Heidelberg
DE

E-Mail: juergen.hartmann@springer.com

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