Molecular Mechanisms of Parasite Invasion

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160,49 

Subcellular Biochemistry 47

ISBN: 1441926836
ISBN 13: 9781441926838
Herausgeber: Barbara A Burleigh/Dominique Soldati
Verlag: Springer Verlag GmbH
Umfang: xx, 237 S., 48 s/w Illustr., 4 farbige Illustr., 237 p. 52 illus., 4 illus. in color.
Erscheinungsdatum: 19.11.2010
Auflage: 1/2010
Produktform: Kartoniert
Einband: Kartoniert
Artikelnummer: 961876 Kategorie:

Beschreibung

All of the parasitic organisms highlighted in this new book represent medically important human pathogens that contribute significantly to the global burden of disease. As such there is intense interest in understanding the molecular basis of infection by these pathogensnot only with regard to their clinical relevance but also the fascinating biology they reveal. For most of the parasites discussed here the ability to penetrate biological barriers and/or to establish intracellular residence is critical to survival of the pathogen in the mammalian hosts. For other parasites, a tissue invasive phenotype is a key virulence determinant. In the ensuing 18 chapters, select members of this diverse set of protozoan parasites, as well as some examples of the extremely reduced fungal parasites classified as Microsporidia, are discussed within the context of the fascinating molecular strategies employed by these organisms to migrate across biological barriers and to establish residence within target host cells.

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