Long Non-coding RNAs in Human Disease

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Current Topics in Microbiology and Immunology 394

ISBN: 3319795511
ISBN 13: 9783319795515
Herausgeber: Kevin V Morris
Verlag: Springer Verlag GmbH
Umfang: viii, 262 S.
Erscheinungsdatum: 22.04.2018
Auflage: 1/2016
Produktform: Kartoniert
Einband: KT

This volume focuses on the roles of long non-coding RNAs (lncRNAs) in contexts ranging from human cancers to cardiovascular disease and ageing. The role of lncRNAs in X-inactivation and those lncRNAs derived from pseudogenes, past retroelements integrated within the human genome, as well as the role these pseudogene-derived lncRNAs play in cancer development are discussed in detail. Further, the book examines the function of lncRNAs in diseases such as diabetes, in smooth muscle formation, and in the modulation of nuclear receptors, as well as in connection with perspectives on the development of personalized therapeutics. It offers an appealing and insightful resource for scientists and clinicians alike.

Artikelnummer: 5461235 Kategorie:

Beschreibung

This volume focuses on the roles of long non-coding RNAs (lncRNAs) in contexts ranging from human cancers to cardiovascular disease and ageing. The role of lncRNAs in Xinactivation and those lncRNAs derived from pseudogenes, past retroelements integrated within the human genome, as well as the role these pseudogenederived lncRNAs play in cancer development are discussed in detail. Further, the book examines the function of lncRNAs in diseases such as diabetes, in smooth muscle formation, and in the modulation of nuclear receptors, as well as in connection with perspectives on the development of personalized therapeutics. It offers an appealing and insightful resource for scientists and clinicians alike.

Autorenporträt

Kevin Morris is an Associate Professor at the Department of Molecular and Experimental Medicine, The Scripps Research Institute in La Jolla, CA, USA. The responsible series editor is Peter K. Vogt, The Scripps Research Institute in La Jolla, CA, USA.

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