Produktbild: Inflammasome Signaling and Bacterial Infections

Inflammasome Signaling and Bacterial Infections

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Current Topics in Microbiology and Immunology 397

ISBN: 3319822853
ISBN 13: 9783319822853
Herausgeber: Steffen Backert
Verlag: Springer Verlag GmbH
Umfang: xi, 282 S., 1 s/w Illustr., 28 farbige Illustr., 282 p. 29 illus., 28 illus. in color.
Erscheinungsdatum: 07.06.2018
Auflage: 1/2018
Produktform: Kartoniert
Einband: Kartoniert

This volume details our current understanding of the architecture and signaling capabilities of known canonical and non-canonical inflammasome complexes and highlights their action, in particular in response to infection with important bacterial model organisms and the corresponding disease pathologies. The first chapters review new insights into the assembly and structures of inflammasome components and emphasize general strategies of up- and downstream signaling events. In addition, the authors specifically discuss the composition and activity of inflammasomes during infection with various gut pathogens (Salmonella, Shigella, Yersinia, Listeria and Helicobacter), respiratory pathogens (Mycobacterium, Legionella, Burkholderia and Streptococcus) as well as skin and soft tissue pathogens (Francisella and Staphylococcus). The discoveries presented provide a better understanding of the cellular and molecular biology of inflammasomes, which will pinpoint important new therapeutic targets for the treatment and prevention of multiple infectious diseases in the future. It is a valuable resource for students, scientists and clinicians, providing up-to-date information on this emerging research topic.

Artikelnummer: 5459673 Kategorie:

Beschreibung

Autorenporträt

Steffen Backert is a professor at Erlangen/Nuremberg University (Germany), Chair of Microbiology.

Herstellerkennzeichnung:


Springer Verlag GmbH
Tiergartenstr. 17
69121 Heidelberg
DE

E-Mail: juergen.hartmann@springer.com

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