Glucose-sensing Receptor in Pancreatic Beta-cells
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| ISBN: |
9811300011 |
| ISBN 13: |
9789811300011 |
| Herausgeber: |
Itaru Kojima |
| Verlag: |
Springer Verlag GmbH |
| Umfang: |
v, 71 S., 8 s/w Illustr., 7 farbige Illustr., 71 p. 15 illus., 7 illus. in color. |
| Erscheinungsdatum: |
19.12.2019 |
| Auflage: |
1/2019 |
| Produktform: |
Gebunden/Hardback |
| Einband: |
Gebunden |
Since the 1970s, there has been much discussion about the „glucoreceptor“ and „substrate site“ and which of these two is the dominant theory, but new findings on the glucose-sensing receptor have now shed new light on the „glucoreceptor theory.“This volume reviews recent advances concerning the glucose-sensing receptor in pancreatic beta-cells.The history of research into pancreatic beta-cells is long and complex; accordingly, the first chapters present the history of this field and explain the hypothesis of insulin secretion mechanisms: „glucoreceptor theory“. Subsequent chapters examine the function and activity of the glucose-sensing receptor in pancreatic beta-cells, such as identification, channel pathway, receptor signal and physiological role. Readers will gain a thorough understanding of the glucose-sensing receptor and glucose metabolism in pancreatic beta-cells, new insights into the pathophysiology of diabetes, and learn about new targets for the treatment of diabetes.