Produktbild: Fc Mediated Activity of Antibodies

Fc Mediated Activity of Antibodies

Lieferzeit: Lieferbar innerhalb 14 Tagen

90,94 €

inkl. 7 % MwSt. zzgl. Versandkosten

Structural and Functional Diversity, Current Topics in Microbiology and Immunology 423

ISBN: 3030310558
ISBN 13: 9783030310554
Herausgeber: Jeffrey V Ravetch/Falk Nimmerjahn
Verlag: Springer Verlag GmbH
Umfang: vii, 150 S., 2 s/w Illustr., 12 farbige Illustr., 150 p. 14 illus., 12 illus. in color.
Erscheinungsdatum: 19.09.2020
Auflage: 1/2020
Produktform: Kartoniert
Einband: Kartoniert

This volume explores several aspects of how antibodies mediate their activity in vivo, ranging from cancer immunotherapy to autoimmunity, infection, and vaccination. Divided into seven chapters, it provides in-depth insights into how antibodies and especially the antibody fragment crystallizable (Fc) domain modulate immune responses and antibody activity. The book begins by discussing evolutionary aspects of how the family of Fc receptors that are the key molecules for antibody activity evolved. In turn, it addresses the molecular and cellular pathways underlying IgG activity in cancer immunotherapy, and focuses on how IgG glycosylation regulates IgG and IgE activity in autoimmunity, allergy and infection. In closing, it presents strategies for developing novel antibody-based vaccination approaches. The book is intended for a very broad readership, including graduate students, postdocs and principal investigators with a basic grasp of immunology.

Artikelnummer: 9865644 Kategorie:

Beschreibung

Autorenporträt

Jeffrey V. RavetchTheresa and Eugene M. Lang ProfessorDepartment Leonard Wagner Laboratory of Molecular Genetics and ImmunologyRockefeller University1230 York Avenue, Box 98New York, NY 10021, USAravetch@mail.rockefeller.edu Falk NimmerjahnProfessor for Immunology and GeneticsChairman of the Institute of GeneticsHead of the Department of BiologyDepartment of BiologyUniversity of Erlangen-NuernbergErwin-Rommelstr. 391058 Erlangen, Germanyfalk.nimmerjahn@fau.de

Herstellerkennzeichnung:


Springer Verlag GmbH
Tiergartenstr. 17
69121 Heidelberg
DE

E-Mail: juergen.hartmann@springer.com

Das könnte Ihnen auch gefallen …