Computational Modeling of Drugs Against Alzheimers Disease

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117,69 

Neuromethods 132

ISBN: 1493984756
ISBN 13: 9781493984756
Herausgeber: Kunal Roy
Verlag: Humana Press
Umfang: xvii, 645 S., 64 s/w Illustr., 158 farbige Illustr., 645 p. 222 illus., 158 illus. in color.
Erscheinungsdatum: 10.08.2018
Auflage: 1/2018
Produktform: Kartoniert
Einband: Kartoniert

This volume describes different computational methods encompassing ligand-based approaches (QSAR, pharmcophore), structure-based approaches (homology modeling, docking, molecular dynamics simulation), and combined approaches (virtual screening) with applications in anti-Alzheimer drug design. Different background topics like molecular etiologies of Alzheimer’s disease, targets for new drug development, and different cheminformatic modeling strategies are covered for completeness. Special topics like multi-target drug development, natural products, protein misfolding, and nanomaterials are also included in connection with computational modeling of anti-Alzheimer drug development. In Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Cuttingedge and authoritative, Computational Modeling of Drugs Against Alzheimer’s Disease is a valuable resource for learning about the latest computational techniques used to study this disease.

Artikelnummer: 6778727 Kategorie:

Beschreibung

This volume describes different computational methods encompassing ligand-based approaches (QSAR, pharmcophore), structure-based approaches (homology modeling, docking, molecular dynamics simulation), and combined approaches (virtual screening) with applications in anti-Alzheimer drug design. Different background topics like molecular etiologies of Alzheimer's disease, targets for new drug development, and different cheminformatic modeling strategies are covered for completeness. Special topics like multi-target drug development, natural products, protein misfolding, and nanomaterials are also included in connection with computational modeling of anti-Alzheimer drug development. In Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory.  Cuttingedge and authoritative, Computational Modeling of Drugs Against Alzheimer's Disease is a valuable resource for learning about the latest computational techniques used to study this disease. 

Autorenporträt

Dr. Kunal Roy is a Professor in the Department of Pharmaceutical Technology, Jadavpur University, Kolkata, India. He has been a recipient of Commonwealth Academic Staff Fellowship (University of Manchester, 2007) and Marie Curie International Fellowship (University of Manchester, 2013). The field of his research interest is QSAR and Molecular Modeling with application in Drug Design and Ectoxicological Modeling. Dr. Roy has published more than 250 research papers in refereed journals (current SCOPUS h index 35). He has also coauthored two QSAR related books, edited two QSAR books and published ten book chapters. Dr. Roy serves in different capacities in the Editorial Boards of several International Journals.

Herstellerkennzeichnung:


Humana Press in Springer Science + Business Media
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14197 Berlin
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E-Mail: juergen.hartmann@springer.com

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