Co-Existence and Co-Release of Classical Neurotransmitters
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| ISBN: |
0387096213 |
| ISBN 13: |
9780387096216 |
| Herausgeber: |
Rafael Gutierrez |
| Verlag: |
Springer Verlag GmbH |
| Umfang: |
xx, 236 S., 19 s/w Illustr., 16 farbige Illustr., 2 s/w Tab., 236 p. 35 illus., 16 illus. in color. |
| Erscheinungsdatum: |
04.12.2008 |
| Auflage: |
1/2008 |
| Produktform: |
Gebunden/Hardback |
| Einband: |
GEB |
Until recently, many neuroscientists were skeptical of the idea that classical neurotransmitters could be co-released from neurons. It is now common knowledge, though, that the „one neuron, one neurotransmitter“ postulate is the exception rather than the rule. Co-Existence and Co-Release of Classical Neurotransmitters provides readers with a comprehensive overview of research from the worldâEuros leading neuroscience authors, all of whom have discovered and studied the co-existence or co-release of several pairs of neurotransmitters in neural networks. Their reviews include novel aspects of transmitter combinations, such as NA-ACh, monoamines-glutamate, ACh-glutamate, cross-talk between monoamines, GABA and ATP, and various combinations of aminoacid transmitters. CoExistence and CoRelease of Classical Neurotransmitters will be particularly useful to neuroscience graduate students, academics, and researchers in synaptic physiology and synaptic plasticity. This book is the first of its kind to center on the timely issue of corelease of neurotransmitters, and serves as an important contribution to the reconsideration of this idea in other brain regions. About the Editor: Dr. Rafael Gutiérrez was among the first to study the physiological impact of the co-existence of glutamate and GABA in the hippocampus, particularly the developmental and activity-dependent expression of GABAergic markers in granule cells. Since 1997, Dr. Gutiérrez has been a professor of neurosciences at the Center for Research and Advanced Studies (CINVESTAV) in Mexico City. He recieved his PhD in Neurosciences from the National University of Mexico in 1993 and, under the prestigious Alexander von Humboldt Research Scholarship, worked for three years with pathophysiology expert Uwe Heinemann in Germany.
Beschreibung
InhaltsangabeCoexistence of Neuromessenger Molecules -- A Perspective.-: Out of One, Many.- Mechanisms of Synapse Formation: Activity-Dependent Selection of Neurotransmitters and Receptors.- Co-Release of Norepinephrine and Acetylcholine by Mammalian Sympathetic Neurons: Regulation by Target-Derived Signaling.- GABA, Glycine, and Glutamate Co-Release at Developing Inhibitory Synapses.- GABA is the Main Neurotransmitter Released from Mossy Fiber Terminals in the Developing Rat Hippocampus.- Postsynaptic Determinants of Inhibitory Transmission at Mixed GABAergic/Glycinergic Synapses.- Glutamate Co-Release by Monoamine Neurons.- Dopamine and Serotonin Crosstalk Within the Dopaminergic and Serotonergic Systems.- The Dual Glutamatergic/GABAergic Phenotype of Hippocampal Granule Cells.- Synaptic Co-Release of ATP and GABA.- The Co-Release of Glutamate and Acetylcholine in the Vertebrate Nervous System.- Colocalization and Cotransmission of Classical Neurotransmitters: An Invertebrate Perspective.-: Out of Many, One.
Inhaltsverzeichnis
Mechanisms of synapse formation: Activity-dependent selection of neurotransmitters and receptors.- Regulation of cardiac excitation and inhibition through modulation of sympathetic co-transmission.- The dual glutamatergic/GABAergic phenotype of the hippocampal granule cells.- Glycine-GABA-glutamate co-transmission at developing central auditory synapses.- GABA actions at an excitatory synapse in the hippocampus.- Glutamate co-release by monoamine neurons.- Postsynaptic determinants of inhibitory transmission at mixed GABAergic/glycinergic synapses.- GABA is the main neurotransmitter released from mossy fiber terminals in the developing hippocampus.- The corelease of glutamate and acetylcholine in vertebrate central nervous system.- Co-release of GABA and ATP.- Interactions within Catecholamine Systems: co-release of dopamine and serotonin.- Colocalization and Cotransmission of Classical Neurotransmitters: An Invertebrate Perspective.- Out of many, one: Integration of co-released neurotransmitters.
