Advances in Chronic Lymphocytic Leukemia

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Advances in Experimental Medicine and Biology 792

ISBN: 1461480507
ISBN 13: 9781461480501
Herausgeber: Sami Malek
Verlag: Springer Verlag GmbH
Umfang: xi, 334 S., 1 s/w Illustr., 24 farbige Illustr., 334 p. 25 illus., 24 illus. in color.
Erscheinungsdatum: 07.09.2013
Auflage: 1/2013
Produktform: Gebunden/Hardback
Einband: GEB

In this book, the authors focus on crucial aspects of chronic lymphocytic leukemia (CLL) pathogenesis and delineate the known and unknown in CLL to inform readers and to motivate out of the box thinking in future CLL research.

Artikelnummer: 4893993 Kategorie:

Beschreibung

InhaltsangabePreface.- B-cell receptor and antigens in CLL.- The CLL cell microenvironment.- Acquired genomic copy number aberrations in CLL.- Recurrent gene mutations in CLL.- TP53 aberrations in CLL.- Gene expression and epigenetic deregulation.- Apoptosis deregulation in CLL.- Richter's Syndrome.- Molecular biomarkers in chronic lymphocytic leukemia.- Critical Signal Transduction Pathways in CLL.- Immunotherapies in CLL.- Novel therapeutic agents in CLL.- Inherited susceptibility to CLL.- miR deregulations in CLL.- Index.

Autorenporträt

Sami N. Malek is an Associate Professor at the Department of Internal Medicine at the University of Michigan Health System. Dr. Malek's research interests include basic and translational questions in Leukemia and Lymphoma. Well known in the field of CLL, Dr. Malek is well-published in the area and is invited to international conferences and seminars to give talks on the topic.

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