Adenosine

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213,99 

A Key Link between Metabolism and Brain Activity

ISBN: 148998755X
ISBN 13: 9781489987556
Herausgeber: Susan Masino/Detlev Boison
Verlag: Springer Verlag GmbH
Umfang: xvi, 680 S.
Erscheinungsdatum: 19.09.2014
Auflage: 1/2014
Produktform: Kartoniert
Einband: Kartoniert

Following on new understanding of its influence in dopaminergic disorders, sleep and epilepsy, this book collects recent research on regulating the influence of adenosine, outlines clinical implications, and highlights emerging adenosine-based therapies.

Artikelnummer: 7247502 Kategorie:

Beschreibung

Autorenporträt

InhaltsangabeAdenosine and metabolism - a brief historical note.- Adenosine metabolism, adenosine kinase and evolution.- Adenosine and energy metabolism - relationship to brain bioenergetics.- Adenosine and autocrine metabolic regulation of neuronal activity.- Physiologic and metabolic regulation of adenosine - mechanisms.- The double edged sword: gaining adenosine at the expense of ATP. How to balance the books.- Downstream pathways of adenosine.- Astrocytic ATP release.- Role of striatal A2A receptor subpopulations in neurological disorder.- Sleep and adenosine: human studies.- Adenosine and Other Purinergic Products in Circadian Timing.- Adenosine in the immune system.- The bioenergetics network of adenosine in hibernation, sleep and thermoregulation.- Adenosine and stroke.- The many roles of adenosine in traumatic brain injury.- Therapeutic Perspectives of Adenosine Receptor Compounds in Functional Restitutions after Spinal Cord Injury.- Adenosine and pain.- Symptomatic and neuroprotective effects of A2A receptor antagonists in Parkinson's Disease.- Adenosine receptors and Alzheimer's Disease.- Adenosine receptors in Huntington's Disease.- Adenosine and Multiple Sclerosis.- Adenosinergic perspectives on schizophrenia - Opportunity for an integrative synthesis.- The role of adenosine in the ventral striatal circuits regulating behavioral activation and effort-related decision making: Importance for normal and pathological aspects of motivation.- Adenosine and autism:  Physiological symptoms and metabolic opportunities.- Stress, Brain Adenosine Signaling, and Fatigue-Related Behavioral Processes.- Disruption of adenosine homeostasis in epilepsy and therapeutic adenosine augmentation.- Ketogenic Diet and Epilepsy: The Role of Adenosine.- Silk - a biocompatible and biodegradable biopolymer for therapeutic adenosine delivery.- Anatomical Distribution of Nucleoside System in the Human Brain and Implications for Therapy.

Herstellerkennzeichnung:


Springer Verlag GmbH
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69121 Heidelberg
DE

E-Mail: juergen.hartmann@springer.com

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