Polycystic Ovary Syndrome

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Current Controversies – from the Ovary to the Pancreas, Contemporary Endocrinology

ISBN: 1588298310
ISBN 13: 9781588298317
Herausgeber: Andrea Dunaif/R Jeffrey Chang/Stephen Franks et al
Verlag: Humana Press
Umfang: xv, 350 S.
Erscheinungsdatum: 19.02.2008
Auflage: 1/2008
Produktform: Gebunden/Hardback
Einband: GEB

All four editors of this title are extremely prominent in the field of PCOS. Although they are all U.S.-based, they are internationally renowned. The book includes the latest diagnostic criteria for PCOS, and comprises the most up to date information about the genetic features and pathogenesis of PCOS. The diagnostic criteria for PCOS took shape in 1990 following an NIH conference co-organized by Dr. Dunaif, resulting in her classic volume, Polycystic Ovary Syndrome (1992). That title recommended diagnostic criteria of hyperandrogenism and chronic anovlulation with the exclusion of specific disorder of the ovary, adrenal, and pituitary. These criteria dominated the field but were revised in 2003 by a working group of international experts at a conference in Rotterdam. Since then, it has become increasingly clear over the past several years that PCOS is a complex genetic disease resulting from the interaction of susceptibility genes and environmental factors. This volume critically reviews the methodological approaches and the evidence for various PCOS susceptibility genes. Additional familial phenotypes of PCOS and their potential genetic basis are also discussed. In all, this title is comprehensive and replete with the latest in expert recommendations on PCOS. This expert opinion remains critical to guiding practice in PCOS because sufficient data for evidence-based guidelines remains scarce.

Artikelnummer: 1119108 Kategorie:

Beschreibung

InhaltsangabeSection I: The Polycystic Ovary.- 1 Ovarian Function and Folliculogenesis in PCOS.- 2 Accounting for the Follicle Population in the Polycystic Ovary.- 3 What is Appropriate Imaging of the Polycystic Ovary?.- 4 PCO vs PCOS: A Necessary Distinction? Section II: Genetic and Environmental Factors in PCOS.- 5 Genetics of PCOS.- 6 Fetal Origins of PCOS.- 7 Precursors of PCOS.- 8 Variations in the Expression of the PCOS Phenotype.- 9 Acquired PCOS: Epilepsy and the Role of Antiepileptic Drugs.- 10 Recommendations for the Early Recognition and Prevention of PCOS.- Section III: Metabolic Consequences of PCOS.- 11 Insulin Action and Secretion in PCOS.- 12 Long-term Health Risks of PCOS.- 13 Therapy Targeting Metabolic Defects in PCOS.- 14 Mechanisms and Treatment of Obesity in PCOS.- 15 Metabolic and Reproductive Effects of Statins in PCOS.- 16 Recommended Therapies for Metabolic Defects in PCOS.- Section IV: Hyperandrogenism in PCOS.- 17 Pathogenesis of Hyperandrogenism.- 18 Recommended Treatment Modalities for Hyperandrogenism.- Section V: Ovulation Induction in PCOS.- 19 Effective Regimens for Ovulation Induction in PCOS.- 20 Pregnancy in PCOS.- Section VI Diagnostic Criteria.- 21 Impact of Diagnostic Criteria: NICHD vs Rotterdam.- 22 Reassessment of Diagnostic Criteria and Recommendations.

Autorenporträt

InhaltsangabeFolliculogenesis in Polycystic Ovaries.- Accounting for the Follicle Population in the Polycystic Ovary.- What Is the Appropriate Imaging of the Polycystic Ovary.- Polycystic Ovary Versus Polycystic Ovary Syndrome.- Genetic Analyses of Polycystic Ovary Syndrome.- Fetal Origins of Polycystic Ovary Syndrome.- Pubertal Precursors of the Polycystic Ovarian Syndrome.- Variations in the Expression of the Polycystic Ovary Syndrome Phenotype.- Acquired Polycystic Ovary Syndrome.- Recommendations for the Early Recognition and Prevention of Polycystic Ovary Syndrome.- Insulin Action and Secretion in Polycystic Ovary Syndrome.- Polycystic Ovary Syndrome and the Metabolic Syndrome Long-Term Risks.- Insulin Sensitizers Targeting Metabolic and Reproductive Consequences in Polycystic Ovary Syndrome.- Mechanisms and Treatment of Obesity in Polycystic Ovary Syndrome.- Metabolic and Endocrine Effects of Statins in Polycystic Ovary Syndrome.- Recommended Therapies for Metabolic Defects in Polycystic Ovary Syndrome.- Pathogenesis of Hyperandrogenism in Polycystic Ovary Syndrome.- Recommended Treatment Modalities for Hyperandrogenism.- Effective Regimens for Ovulation Induction in Polycystic Ovary Syndrome.- Pregnancy in Polycystic Ovary Syndrome.- Impact of Diagnostic Criteria.

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